Results 71 to 80 of about 819,681 (335)

Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]

open access: yes, 1998
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Bosbach, R.   +3 more
core   +1 more source

Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling

open access: yesJournal of Cellular and Molecular Medicine, 2013
As a traditional anti‐inflammatory Chinese herbal medicine, Alkaloid berberine has been recently reported to exhibit anti‐tumour effects against a wide spectrum of cancer. However, the mechanism was largely unknown.
Junfang Zhang   +11 more
semanticscholar   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

Inflammatory fibroid polyp of the ileum presenting with small bowel obstruction in an adult patient: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction Inflammatory fibroid polyps are rare benign tumors of the gastrointestinal tract with the gastric antrum being the most common site, followed by the ileum. Histogenesis is still unknown and controversial.
Toydemir Toygar
doaj   +1 more source

Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]

open access: yes, 2002
Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
core   +2 more sources

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

open access: yesAdvanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang   +11 more
wiley   +1 more source

First reports of computed tomographic colonography for the screening of colorectal polyps in acromegalic patients [PDF]

open access: yes, 2008
*Aim:* To analyze the CTC performance for the screening of colorectal polyps in acromegalic patients. *Materials and Methods:* A prospective study of 21 acromegalic patients, 12 male and 9 female, average age 49, who underwent CTC ...
Anke Boeving   +7 more
core   +1 more source

Unintended targeting of Dmp1-Cre reveals a critical role for Bmpr1a signaling in the gastrointestinal mesenchyme of adult mice [PDF]

open access: yes, 2017
Cre/loxP technology has been widely used to study cell type-specific functions of genes. Proper interpretation of such data critically depends on a clear understanding of the tissue specificity of Cre expression. The Dmp1-Cre mouse, expressing Cre from a
Burclaff, Joseph   +4 more
core   +2 more sources

Curcumin suppresses intestinal polyps in APC Min mice fed a high fat diet

open access: yesPathobiology of Aging & Age-related Diseases, 2011
Colorectal cancer (CRC) is a leading cause of cancer deaths in the United States. Various risk factors have been associated with CRC including increasing age and diet.
C. Pettan-Brewer   +3 more
semanticscholar   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

open access: yesAdvanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang   +12 more
wiley   +1 more source

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