Results 221 to 230 of about 1,734,969 (325)

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Comment on Catanzaro et al. Risk Factors for Recurrence of Primary Sclerosing Cholangitis after Liver Transplantation: Single-Center Data. J. Pers. Med. 2024, 14, 222. [PDF]

J Pers Med
Mammadov RA, Roest HP, Peppelenbosch MP, van der Laan LJW.   +3 more
europepmc   +1 more source

Clinicopathological manifestations and treatment of intestinal transplant-associated microangiopathy

Bone Marrow Transplantation, 2009
Y. Inamoto, M. Ito, R. Suzuki, T. Nishida, H. Iida, A. Kohno, M. Sawa, M. Murata, S. Nishiwaki, Taku Oba, M. Yanada, T. Naoe, Ryoichi Ichihashi, M. Fujino, T. Yamaguchi, Y. Morishita, N. Hirabayashi, Y. Kodera, K. Miyamura   +18 more
semanticscholar   +1 more source

Intestinal and multiple organ transplantation [PDF]

, 1995
Abu-Elmagd, K, Casavilla, A, Reyes, J, Selby, R, Starzl, TE, Todo, S, Tzakis, A   +6 more
core  

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Assessment of the Intestinal CYP3A Contribution to Drug Interactions with Extended-Release Tacrolimus (LCPT) Using Grapefruit Juice. [PDF]

Clin Pharmacol Drug Dev
Alabi A, Kerr JS, Shah M, Khan A, Ma JD, Suhandynata RT, Momper JD, Tsunoda SM.   +7 more
europepmc   +1 more source

Current status of intestinal transplantation. [PDF]

, 1994
Abu-Elmagd, K, Reyes, J, Starzl, TE, Todo, S, Tzakis, A   +4 more
core  

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Microbiota transplants: the concept of 'microbiome mismatching' explored. [PDF]

Signal Transduct Target Ther
Mullish BH, Roberts LA, Williams HRT.
europepmc   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source