Results 101 to 110 of about 844,508 (249)

Cost-effectiveness of intestinal transplantation for adult patients with intestinal failure: a simulation study

, 2015
Background: Home parenteral nutrition (HPN) and intestinal transplantation (ITx) are the 2 treatment options for irreversible intestinal failure (IF). Objective: This study simulated the disease course of irreversible IF and both of these treatments HPN ...
Haveman, Jan Willem, Gerard Dijkstra, Krabbe, Paul F. M.; id_orcid, Dijkstra, Gerard, Roskott, Anne Margot, Rings, Edmond H. H. M., Rutger J Ploeg, Edmond Hhm Rings, Mireille J Serlie, Dijkstra, Gerard; id_orcid, Groen, Henk; id_orcid, Jan Willem Haveman, Geert Wanten, Krabbe, Paul F. M., Wanten, Geert, Groen, Henk, Anne Margot Roskott, Paul Fm Krabbe, Serlie, Mireille J., Henk Groen, Ploeg, Rutger J.   +20 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

A Clinical Study of Decellularized Tissue Engineering Hyaline Cartilage Graft (dLhCG) for Articular Cartilage Repair

Advanced Science, EarlyView.
ABSTRACT Current clinical approaches for knee cartilage repair are often limited by hypertrophy and fibrosis in the regenerated tissues. A decellularized tissue‐engineered hyaline cartilage graft (dLhCG), composed of a type II collagen‐based extracellular matrix, has been developed to overcome this limitation.
Zhen Zhang, Gong Cheng, Wenyong Fei, Qiuzhen Liang, Liang Zhang, Kegui Liu, Jihang Dai, Bo Cong, Xu Hu, Zhonglian Wu, Jialu Zhang, Jinlan Cui, Hang Yao, Dong‐An Wang, Jingcheng Wang, Tao Sun, Jiang Zheng   +16 more
wiley   +1 more source

Indications for intestinal transplantation

, 2015
Home parenteral nutrition is the primary treatment for patients with chronic intestinal failure. These patients have a high probability of long-term survival, but they may have also an increased risk of death due to factors related to parenteral ...
L. Pironi, PIRONI, LORIS
core   +2 more sources

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Intestinal permeability in allogeneic hematopoietic stem cell transplantation: A comprehensive review of measurement methods, clinical determinants and prognostic significance

Hematology, Transfusion and Cell Therapy
The role of intestinal permeability in patients undergoing allogeneic hematopoietic stem cell transplantation remains unclear. This narrative review aimed to critically analyze the available evidence regarding the dynamics, predictors, and prognostic ...
Alexandre Soares Ferreira Junior, Bianca Fernanda Rodrigues da Silva, Nathalia Linares Silva, Mariana Trovao da Silva, Rozana Mesquita Ciconelli, Phillip Scheinberg, Gislane Lelis Vilela de Oliveira   +6 more
doaj   +1 more source

Intestinal transplantation: advances in immunosuppression and surgical techniques

, 2003
Campath-1H is being used as induction immunosuppression for intestinal/multivisceral transplantation. Patient and graft survival in this preliminary experience is similar to previous studies but there has been a significant decrease in the incidence and ...
Tryphonopoulos, P, Kato, T, De Faria, W, Madariaga, J, Nishida, S, Thompson, J F, Levi, D M, Tzakis, A G, Nery, J R, Mittal, N, Ruiz, P   +10 more
core   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source