Results 171 to 180 of about 1,797,820 (320)

Asymptomatic Migration of an Amplatzer Vascular Plug into the Distal Abdominal Aorta

Vascular Specialist International
Geert Maleux, Laurens J. Ceulemans, Tim Vanuytsel, Diethard Monbaliu, Jacques Pirenne   +4 more
doaj   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Intestinal Transplantation in a Country Without Home Parenteral Nutrition: The Largest Report from the Middle East. [PDF]

Turk J Gastroenterol, 2022
Nikoupour H, Khosravi MB, Vatankhah P, Shafiekhani M, Shamsaeefar A, Arasteh P, Anbardar MH, Eghbal MH, Sahmeddini MA, Khalili F, Firoozifar M, Tehran SG, Nikeghbalian S.   +12 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Intestinal reengineering: Scientific advances in intestinal transplantation. [PDF]

World J Gastrointest Surg
Rong Y, Nie CY, Zhou JD, Wang ZC, Wu DL, Wu SW, Xie ZY.   +6 more
europepmc   +1 more source

Late Bleeding Episodes Following Intestinal Transplantation: It Is Not Always Rejection or Infection. [PDF]

JPGN Rep, 2022
Singh H, Selvarajan L, Ong SY, Ali S, Sharif K, Mirza D, Gupte G.   +6 more
europepmc   +1 more source

Intestine transplantation

Zdravniški Vestnik, 2011
Background: Intestine transplantation is reserved for patients with irreversible intestinal failure due to SGS requiring TPN without possibility of discontinuation. In SGS, the patient’s small intestine is unable to maintain an adequate nutritional status or fluid and electrolyte balance on enteral feeding, resulting in poor growth and development. Due
openaire   +1 more source

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

Intestinal transplantation in Familial Adenomatous Polyposis. [PDF]

Fam Cancer
Canovai E, Upponi S, Amin I.
europepmc   +1 more source

A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury

Advanced Science, EarlyView.
A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang, Hao Hu, Yijun Li, Lintao Hu, Chenhui Gu, Yiwei Zhu, Jing Huang, Na Li, Shuqi Jiang, Shouyan Zu, Jiachen Xu, Yining Wang, Ke Yang, Pengfei Chen, Liqing Shangguan, Yongcheng Wang, Shunwu Fan, Xianfeng Lin, Qingqing Wang   +18 more
wiley   +1 more source