Results 41 to 50 of about 98,760 (293)

Multilevel Analysis of the Neovascularization and Integration Process of a Nonvascularized Rectus Fascia Transplantation

Transplantation Direct
Background. Failure to close the abdominal wall after intestinal transplantation (ITx) or multivisceral Tx remains a surgical challenge. An attractive method is the use of nonvascularized rectus fascia (NVRF) in which both layers of the donor abdominal ...
Ewout Muylle, BSc, Arne Maes, MSc, Gert De Hertogh, MD, PhD, Nele Van De Winkel, MD, Greet Kerckhofs, PhD, Antoine Dubois, MD, Vincent Vandecaveye, MD, PhD, Lieven Thorrez, PhD, Ina Hennion, MSc, Marie-Paule Emonds, MD, PhD, Steven Pans, MD, Nathalie P. Deferm, MD, Diethard Monbaliu, MD, PhD, Emilio Canovai, MD, PhD, Tim Vanuytsel, MD, PhD, Jacques Pirenne, MD, PhD, Laurens J. Ceulemans, MD, PhD   +16 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Multivisceral Transplantation as curative Treatment for patients with Diffuse Splanchnic Arterial Ischemia: a case report

Intestinal Failure
Background: Criteria for multivisceral transplantation (MVTx) have broadened. However, diffuse splanchnic arterial ischemia secondary to visceral arterial thrombosis has only been described once.
Caroline Boelhouwer, Aksharaa Iyer, Antoine Dubois, Lawrence Bonne, Geert Maleux, Inge Fourneau, Sabrina Houthoofd, Albert Wolthuis, Philippe Nafteux, Hans Van Veer, Mauricio Sainz, Diethard Monbaliu, Lucas Wauters, Tim Vanuytsel, Laurens J. Ceulemans, Jacques Pirenne   +15 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Alpha1-antitrypsin protects the intestine from ischemia-reperfusion injury in a rat intestinal clamping model

Intestinal Failure
Background: Ischemia-reperfusion injury (IRI) remains a significant hurdle when blood flow is restored to ischemic tissue. Alpha1-antitrypsin (AAT), a serine protease inhibitor, has demonstrated strong anti-inflammatory properties, including inhibition ...
Antoine Dubois, Mathias Clarysse, Ricard Farré, Tine Wylin, Veerle Heetfeld, Emilio Canovai, Tim Vanuytsel, Gert De Hertogh, Jacques Pirenne, Laurens J. Ceulemans   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Function and expression of cystic fibrosis transmembrane conductance regulator after small intestinal transplantation in mice. [PDF]

PLoS ONE, 2013
The secretion function of intestinal graft is one of the most important factors for successful intestinal transplantation. Cystic fibrosis transmembrane conductance regulator (CFTR) mediates HCO3(-) and Cl(-) secretions in intestinal epithelial cells. In
Penghong Song, Wenfeng Song, Xiaosun Liu, Changhai Jin, Haiyang Xie, Lin Zhou, Biguang Tuo, Shusen Zheng   +7 more
doaj   +1 more source

Autologous gastrointestinal reconstructive surgery: complement or alternative to intestinal transplantation

, 2013
PURPOSE OF REVIEW: Autologous intestinal reconstructive surgery has evolved over the past 3 decades from rescue to main surgical procedure in the multidisciplinary approach to short bowel syndrome (SBS) patients with intestinal failure.
Reding, Raymond, Fusaro, Fabio, Hermans, Dominique   +2 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source