Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley +1 more source
Portal bile acid composition and microbiota along the <i>murine</i> intestinal tract exhibit sex differences in physiology. [PDF]
Reichardt F+6 more
europepmc +1 more source
The effect of FK 506 on small intestine allotransplantation in the rat [PDF]
Banner, B+7 more
core
Computational fluid dynamics analyses assess the upstream locomotion performance of anisotropic microrollers with varying height‐to‐width ratios. Observing their successful upstream locomotion in veins, their performance in hepatic circulation is investigated for treating primary liver cancer.
Burak Arslan+8 more
wiley +1 more source
Iron bioaccessibility in raw and cooked foods in vitro using fecal inocula from children and adults. [PDF]
García-Conde Ú+5 more
europepmc +1 more source
CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self‐Supervised Learning
CRCFound is a self‐supervised learning‐based CT image foundation model for colorectal cancer (CRC). Pretrained on 5137 unlabeled CRC CT images, it learns universal feature representations, enabling efficient adaptation to various clinical tasks. The model demonstrates outstanding performance and generalization across multiple diagnostic and prognosis ...
Jing Yang+13 more
wiley +1 more source
Assessment of the effect of prokinetic drugs on transit time and gastrointestinal cleanliness in capsule endoscopy. [PDF]
Rychlik A+3 more
europepmc +1 more source
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui+19 more
wiley +1 more source
Cancer of the Small Intestine [PDF]
openaire +3 more sources
Sudden rupture of recurrent rectal prolapse complicated by small intestine evisceration from anus: a case study. [PDF]
Tian Z+5 more
europepmc +1 more source