Results 241 to 250 of about 683,888 (303)

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Peyer's patch M cells organize an epithelial niche that sustains group 3 innate lymphoid cells and IL-22. [PDF]

Nat Immunol
Cao WHJ, You Y, Wang N, Chaudhry MZ, Yu H, Bell PT, Noye EC, Denman R, Lee B, Waddington A, Ye J, Schreuder J, Huang Q, Tellier J, Curio S, Santiago J, Amann-Zalcenstein D, Jacquelot N, Hickey P, Nutt SL, Seillet C, Hansbro PM, Wimmer VC, Strugnell RA, Tuong ZK, Ritchie ME, Belz GT.   +26 more
europepmc   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

The role of NLRP3 inflammasome in the development of postoperative ileus and its molecular mechanism in male mice. [PDF]

Physiol Rep
Zhang F, Sun B, Guo H.
europepmc   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Prenatal Ultrasound Progression and Postnatal Retrospective Analysis of a Case of Small Intestinal Atresia with Volvulus. [PDF]

Diagnostics (Basel)
Nong L, Wang L, Luo H, Wang Y, Chen C, Xie J, Dai K, Wang J, Xu X.   +8 more
europepmc   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

Limited vertical transmission of microbiomes through the chorioallantoic membrane affects intestine development and metabolic pathways in broiler embryos. [PDF]

Front Microbiol
Al Amaz S, Poudel S, Shahid MAH, Jha R, Mishra B.   +4 more
europepmc   +1 more source

A Case of Congenital Peritoneal Encapsulation Complicated with Left Paraduodenal Hernia Presenting as Recurrent Small Bowel Obstruction. [PDF]

Surg Case Rep
Tominaga N, Oishi K, Takeshita H, Tomiyama T, Ota N, Kubo T, Fukui S, Yamashita M, Kugiyama T, Hara T, Morita M, Fujii M, Yoneda A, Minami S, Kuroki T.   +14 more
europepmc   +1 more source