Results 11 to 20 of about 26,341 (70)

Related Effects of Methamphetamine on the Intestinal Barrier via Cytokines, and Potential Mechanisms by Which Methamphetamine May Occur on the Brain-Gut Axis

Frontiers in Medicine, 2022
Methamphetamine (METH) is an illegal drug widely abused in many countries. Methamphetamine abuse is a major health and social problem all over the world. However, the effects of METH on the digestive system have rarely been reported. Previous studies and
Yuansen Li, Yuansen Li, Deshenyue Kong, Deshenyue Kong, Ke Bi, Ke Bi, Huayou Luo, Huayou Luo, Huayou Luo   +8 more
doaj   +1 more source

N6-Methyladenosine Regulators Promote Malignant Progression of Gastric Adenocarcinoma

Frontiers in Oncology, 2022
N6-methyladenosine (m6A) RNA methylation is dynamically and reversibly regulated by methyltransferases, binding proteins, and demethylases. The restoration of m6A to adenosine could result in demethylation modifications.
Yibin Zhao, Xiao Yan, Yu Wang, Juan Zhou, Yang Yu   +4 more
doaj   +1 more source

Long noncoding RNA TUG1 regulates the progression of colorectal cancer through miR-542-3p/TRIB2 axis and Wnt/β-catenin pathway

Diagnostic Pathology, 2021
Background Colorectal cancer (CRC) is one of the third normal malignancy worldwide. Taurine-upregulated gene 1 (TUG1), a member of long noncoding RNAs (lncRNAs), has been reported to be involved in various cancers.
Quanlin Liu, Wei Zhang, Linshan Luo, Keshun Han, Ruitao Liu, Shue Wei, Xiaoran Guo   +6 more
doaj   +1 more source

Residual cancer is a strong predictor of survival in T3 incidental gallbladder cancer

BMC Surgery, 2022
Background and purpose Index cholecystectomy is insufficient for curing T3 incidental gallbladder cancer (IGC), and once residual cancer (RC) is found, the prognosis is often poor.
Chuan You, Mengyi Xie, Meng Ling, Facai Yang, Yinghe Qiu, Jingdong Li   +5 more
doaj   +1 more source

The role of radiotherapy for patients with primary tracheal carcinoma: two case reports of tracheal carina squamous cell carcinoma and literature review

Frontiers in Oncology
Primary tracheal carcinoma is a rare malignant tumor; its optimal treatment strategy is not yet formally proven. Surgery, especially complete surgical excision, is often considered as the first-line treatment, and chemotherapy has been reported ...
Xiaojing Chang, Xiaojing Chang, Zhesen Tian, Yalei Zhao, Xiaohui Ge, Feng Li, Yu Yang, Huizhi Liu   +7 more
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Identification of Circ_001569 as a Potential Biomarker in the Diagnosis and Prognosis of Pancreatic Cancer

Technology in Cancer Research & Treatment, 2021
Emerging evidence has shown that circular RNAs (circRNAs) serve as a promising biomarker in different malignancies. Specifically, circ_001569 has been found to be upregulated in some types of human gastrointestinal cancer.
Xianbo Shen MM, Yun Chen BS, Jibin Li BS, Huaiyin Huang MM, Chuping Liu MM, Ning Zhou MD   +5 more
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Tectorigenin inhibits Caco-2 human colon cells via NF-κB pathway suppression

Bangladesh Journal of Pharmacology, 2015
Effective immunomodulator and pro-inflammatory cytokine, Tumor necrosis factor-α (TNF-α) are considered to be responsible for connecting autoimmune pathological process and contagious diseases.
Xiao-Yu Dai, Yong-Ming Yu, Zheng-Fang Kong, Yi-Sheng Cao, Dan-Dan Huang, Xiao-Rong Hu, Zuo-An Huang, Yang-Yang Xie, Shun Zhang   +8 more
doaj   +1 more source

lncRNA LINC00460 Silencing Represses EMT in Colon Cancer through Downregulation of ANXA2 via Upregulating miR-433-3p

Molecular Therapy: Nucleic Acids, 2020
Colon cancer (CC), one of the major causes of tumor-associated death, is often presented with a heterogenic pool of cells with unique differentiation patterns. This study explored the functions that LINC00460 displayed in CC by regulating microRNA-433-3p
Weiwen Hong, Hongan Ying, Feng Lin, Ruliang Ding, Weiya Wang, Meng Zhang   +5 more
doaj   +1 more source

Prognostic significance of p27 in colorectal cancer: a meta-analysis and bioinformatics analysis

Frontiers in Oncology
BackgroundIn the past, numerous investigations have delved into the influence of p27 (p27kip) on the prognosis and clinicopathological characteristics of colorectal cancer (CRC), yielding conclusions that are not universally statistically significant ...
Jing Zou, Dong Wang, Gaoping Yin, Kexiang Lu, Kaibin Chang, He Li   +5 more
doaj   +1 more source

Circular RNA circCSPP1 knockdown attenuates doxorubicin resistance and suppresses tumor progression of colorectal cancer via miR-944/FZD7 axis

Cancer Cell International, 2021
Background Circular RNAs (circRNAs) have been reported to play vital roles in colorectal cancer (CRC). However, only a few circRNAs have been experimentally validated and functionally described.
Lanlan Xi, Quanlin Liu, Wei Zhang, Linshan Luo, Jingfeng Song, Ruitao Liu, Shue Wei, Yong Wang   +7 more
doaj   +1 more source