Results 71 to 80 of about 156,721 (253)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Small intestine changes, large intestine problems

Trends in Microbiology
Enteric pathogens must overcome host microbiota-mediated colonization resistance to colonize the gut. Radlinski et al. discovered that Salmonella invasion of the small intestine leads to amino acid malabsorption. This increases amino acid availability in the large intestine, fueling Salmonella colonization through amino acid decarboxylation and ...
Deepanshu Singla, Abigail E. Rose, Wenhan Zhu   +2 more
openaire   +3 more sources

Intestine-specific RNAi knockdown of ins-3 and ins-7 alters srh-234 expression levels in ADL.

, 2016
(A) Representative expression of srh-234p::gfp in adult animals after feeding either ins-3(RNAi) or control RNAi. Feeding RNAi was performed in sid-1(pk3321)him-5(e1409) mutants with the stably integrated oyIs56 transgene carrying the intestine::sid-1 ...
Ari Winbush (651727), Jeremy Grubbs (3144156), Alexander M. van der Linden (240030), Aja McDonagh (3144159), Dominic Valdes (3144153), Matthew Gruner (651725)   +5 more
core   +1 more source

A novel marker glycoprotein for the microvillus membrane of surface colonocytes of rat large intestine and its presence in small-intestinal crypt cells [PDF]

, 1988
Murine mAbs were produced against purified microvillus membranes of rat colonocytes in order to establish a marker protein for this membrane. The majority of antibodies binding to the colonic microvillus membrane recognized a single protein with a mean ...
B Stieger, Marxer, A., A Marxer, Fransen, J. A., Kedinger, M., J A Fransen, S U Gorr, M Kedinger, Gorr, S. U., Stieger, B., Hauri, H. P., H P Hauri, Stieger B, Marxer A, Gorr SU, Kedinger M, Fransen JA, Hauri HP   +17 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Identification of autophagy receptors for the Crohn’s disease-associated adherent-invasive Escherichia coli

Frontiers in Cellular and Infection Microbiology
IntroductionCrohn’s disease (CD) is a chronic inflammatory bowel disease, of which the etiology involves genetic, environmental and microbial factors.
Alison Da Silva, Guillaume Dalmasso, Anaïs Larabi, My Hanh Thi Hoang, My Hanh Thi Hoang, Elisabeth Billard, Nicolas Barnich, Hang Thi Thu Nguyen   +7 more
doaj   +1 more source

Acquired acrodermatitis enteropathica after abdominal surgery: Case report

Case Reports, 2019
Introduction: The treatment of acquired acro­dermatitis enteropathica involves zinc supple­mentation; however, further research is required to establsih the optimal dose and duration of the supplementation.
Adriana Giraldo-Villa, Carlos Ernesto Guzmán-Luna   +1 more
doaj   +1 more source

MYL6B drives the capabilities of proliferation, invasion, and migration in rectal adenocarcinoma through the EMT process

Open Life Sciences, 2020
This study was designed to explore the biological significance of myosin light chain 6B (MYL6B) in rectal adenocarcinoma.
Li Jin-Liang, Wang Zai-Qiu, Sun Xiao-Li
doaj   +1 more source

RESECTION OF INTESTINE. [PDF]

The Lancet, 1898
n ...
openaire   +1 more source