Results 91 to 100 of about 544,707 (268)

ATF family members as therapeutic targets in cancer: From mechanisms to pharmacological interventions

Pharmacological Research
The activating transcription factor (ATF)/ cAMP-response element binding protein (CREB) family represents a large group of basic zone leucine zip (bZIP) transcription factors (TFs) with a variety of physiological functions, such as endoplasmic reticulum (
Xueyao Zhang, Zhijia Li, Xiaochun Zhang, Ziyue Yuan, Lan Zhang, Peng Miao   +5 more
doaj   +1 more source

Celecoxib and rofecoxib have different effects on small intestinal ischemia/reperfusion injury in rats

Frontiers in Pharmacology
IntroductionIntestinal ischemia/reperfusion (I/R) injury is associated with high mortality and there is an unmet need for novel therapies. The intestinal expression of cyclooxygenase-2 (COX-2) increases rapidly after mesenteric I/R, but it is still a ...
Szilvia B. László, Barbara Hutka, Barbara Hutka, András S. Tóth, András S. Tóth, Tamás Hegyes, Zsuzsanna O. Demeter, Zsuzsanna O. Demeter, Arezoo Haghighi, Arezoo Haghighi, Gerda Wachtl, Gerda Wachtl, Ágnes Kelemen, Anna Jakab, Klára Gyires, Klára Gyires, Zoltán S. Zádori, Zoltán S. Zádori   +17 more
doaj   +1 more source

On the Reaction of the Intestine in Relationship to Intestinal Digestion [PDF]

The Journal of Physiology, 1897
B, Moore, D P, Rockwood
openaire   +2 more sources

Small intestine changes, large intestine problems

Trends in Microbiology
Enteric pathogens must overcome host microbiota-mediated colonization resistance to colonize the gut. Radlinski et al. discovered that Salmonella invasion of the small intestine leads to amino acid malabsorption. This increases amino acid availability in the large intestine, fueling Salmonella colonization through amino acid decarboxylation and ...
Deepanshu Singla, Abigail E. Rose, Wenhan Zhu   +2 more
openaire   +3 more sources

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source

Intestinal Lecithinase [PDF]

Nature, 1957
B, EPSTEIN, B, SHAPIRO
openaire   +2 more sources

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Maternal chitosan oligosaccharide supplementation during late gestation and lactation optimizes placental function in sows and intestinal function in 21-day-old IUGR suckling piglets

Frontiers in Veterinary Science
Maternal dietary supplementation with chitosan oligosaccharide (COS) has been considered as a potential intervention to mitigate the occurrence of intrauterine growth restriction (IUGR) and improve postnatal growth.
Xintao Wang, Xintao Wang, Tingting Fang, Tingting Fang, Daiwen Chen, Daiwen Chen, Junning Pu, Junning Pu, Gang Tian, Gang Tian, Jun He, Jun He, Ping Zheng, Ping Zheng, Xiangbing Mao, Xiangbing Mao, Aimin Wu, Aimin Wu, Bing Yu, Bing Yu   +19 more
doaj   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, Accepted Article.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the CARRA, SPARTAN, and PRCSG Advisory Council   +9 more
wiley   +1 more source