Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu +13 more
wiley +1 more source
Aichivirus a Infection Associated with Severe Enteric and Respiratory Disease in a Captive White Lion (<i>Panthera leo</i>). [PDF]
Ding Y +9 more
europepmc +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Untargeted UHPLC-MS/MS analysis of intestines of high-value <i>Apostichopus Japonicus</i>: A proof of concept. [PDF]
Jiang P +5 more
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Comprehensive Proteomics Reveals Acute Osmoregulatory Responses in the Intestine of <i>Oreochromis mossambicus</i> Under Salinity, Alkalinity, and Combined Saline-Alkaline Stress. [PDF]
Su H, Ma D, Fan J, Zhong Z, Zhu H.
europepmc +1 more source
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source
Suspected Microplastic-Like Particles Recovered From Paired Human Small Intestine and Large Intestine Specimens: An Exploratory Post-mortem Study. [PDF]
Radu ET +9 more
europepmc +1 more source
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen +15 more
wiley +1 more source

