Results 71 to 80 of about 700,213 (303)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Small intestine changes, large intestine problems

Trends in Microbiology
Enteric pathogens must overcome host microbiota-mediated colonization resistance to colonize the gut. Radlinski et al. discovered that Salmonella invasion of the small intestine leads to amino acid malabsorption. This increases amino acid availability in the large intestine, fueling Salmonella colonization through amino acid decarboxylation and ...
Deepanshu Singla, Abigail E. Rose, Wenhan Zhu   +2 more
openaire   +3 more sources

Intestine-specific RNAi knockdown of ins-3 and ins-7 alters srh-234 expression levels in ADL.

, 2016
(A) Representative expression of srh-234p::gfp in adult animals after feeding either ins-3(RNAi) or control RNAi. Feeding RNAi was performed in sid-1(pk3321)him-5(e1409) mutants with the stably integrated oyIs56 transgene carrying the intestine::sid-1 ...
Ari Winbush (651727), Jeremy Grubbs (3144156), Alexander M. van der Linden (240030), Aja McDonagh (3144159), Dominic Valdes (3144153), Matthew Gruner (651725)   +5 more
core   +1 more source

Contemporary diagnostic imaging of diseases of the small intestine – magnetic resonance enteroclysis and enterography [PDF]

, 2019
Examination of intestines using methods of magnetic resonance (MR) enterography and MR enteroclysis is currently considered to be the best way to visualise diseases of the small intestine like Crohn’s disease, other inflammatory diseases of the small ...
Dobrowolska-Bąk, Małgorzata, Anna Dubis, Karolina Rożnawska, Rożnawska, Karolina, Małgorzata Dobrowolska-Bąk, Paulina Karcz, Dubis, Anna, Karcz, Paulina   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of autophagy receptors for the Crohn’s disease-associated adherent-invasive Escherichia coli

Frontiers in Cellular and Infection Microbiology
IntroductionCrohn’s disease (CD) is a chronic inflammatory bowel disease, of which the etiology involves genetic, environmental and microbial factors.
Alison Da Silva, Guillaume Dalmasso, Anaïs Larabi, My Hanh Thi Hoang, My Hanh Thi Hoang, Elisabeth Billard, Nicolas Barnich, Hang Thi Thu Nguyen   +7 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Association between dietary calcium intake and constipation in a metabolic syndrome population: evidence from NHANES 2005–2010

Frontiers in Nutrition
BackgroundThe global prevalence of Metabolic Syndrome (MetS) is increasing, primarily characterized by abdominal obesity, which significantly heightens the risk of cardiovascular diseases, gastrointestinal disorders, and cancers. Constipation is a common
Li Zhu, Long Yang, Zonghua Liang, Wen Shi, Ming Ma, Jingbo Chen, Zulipikaer Abdula, Xuchen Gong   +7 more
doaj   +1 more source

Acquired acrodermatitis enteropathica after abdominal surgery: Case report

Case Reports, 2019
Introduction: The treatment of acquired acro­dermatitis enteropathica involves zinc supple­mentation; however, further research is required to establsih the optimal dose and duration of the supplementation.
Adriana Giraldo-Villa, Carlos Ernesto Guzmán-Luna   +1 more
doaj   +1 more source

MYL6B drives the capabilities of proliferation, invasion, and migration in rectal adenocarcinoma through the EMT process

Open Life Sciences, 2020
This study was designed to explore the biological significance of myosin light chain 6B (MYL6B) in rectal adenocarcinoma.
Li Jin-Liang, Wang Zai-Qiu, Sun Xiao-Li
doaj   +1 more source