Results 31 to 40 of about 553,209 (267)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Transcription Factor FXR Activates DHRS9 to Inhibit the Cell Oxidative Phosphorylation and Suppress Colon Cancer Progression

Analytical Cellular Pathology, 2022
Background. Colon cancer is a common gastrointestinal malignancy. It has been discovered that Farnesoid X receptor (FXR) plays an imperative regulatory role in multitype cancers in recent years.
Jinlai Zhao, Yigang Wang, Yang Wang, Jianchao Gao, Haichao Yang, Xiaotang Wu, Hua Li   +6 more
doaj   +1 more source

The clinical value of regional lymphadenectomy for intrahepatic cholangiocarcinoma

Asian Journal of Surgery, 2022
Objective: The aim of this study was to explore the clinical value of lymph node dissection (LND) for intrahepatic cholangiocarcinoma (ICC). Methods: Clinical and pathological data were collected from 147 ICC patients who attended two tertiary centers ...
Facai Yang, Changkang Wu, Zhiyuan Bo, Jian Xu, Bin Yi, Jingdong Li, Yinghe Qiu   +6 more
doaj   +1 more source

Intestinal tuberculosis

Current Opinion in Infectious Diseases, 2009
Intestinal tuberculosis (TB) is increasing due partly to the HIV pandemic. Its clinical presentation mimics inflammatory conditions such as Crohn's disease and malignancies, which are becoming more prevalent, so the diagnosis is problematic.Greater awareness of intestinal TB is needed, both in countries where TB is endemic and developed countries with ...
Donoghue, HD, Holton, J
openaire   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Puncture and catheterization of the ascending colon for succus entericus reinfusion in a patient with a high-output single-lumen stoma: a case report

BMC Surgery
Background High-output enterostomy is a common complication following ostomy procedures. In patients with loop ileostomies, the incidence of dehydration can reach 30%, and it represents the most frequent cause of readmission after ileostomy surgery, with
Sicong Lai, Xijian Zhang, Huanxin Hu, Keming Jiang, Xinzhe Zhao, Hao Zeng, Jia Ke   +6 more
doaj   +1 more source

Macrophages Inability to Mediate Adherent-Invasive E. coli Replication is Linked to Autophagy in Crohn’s Disease Patients

Cells, 2019
The macrophages from Crohn’s Disease (CD) patients are defective to control the replication of CD-associated adherent-invasive E. coli (AIEC). We aimed to identify the host factors associated with AIEC replication focusing on polymorphisms related ...
Anthony Buisson, Clara Douadi, Lemlih Ouchchane, Marion Goutte, Jean-Pierre Hugot, Anaëlle Dubois, Régine Minet-Quinard, Damien Bouvier, Gilles Bommelaer, Emilie Vazeille, Nicolas Barnich   +10 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Gestational Weight Gain and Small for Gestational Age in Obese Women: A Systematic Review and Meta-Analysis

International Journal of Endocrinology, 2023
Objective. This systematic review and meta-analysis evaluates the relationship between gestational weight gain and the risk of small for gestational age in obese pregnant women. Methods.
Wen Chen, Beiyi Li, Kexin Gan, Jing Liu, Yajing Yang, Xiuqin Lv, Huijuan Ma   +6 more
doaj   +1 more source

Predictive Value of Tumor Mutation Burden for PD-1/PD-L1 Inhibitors Treatment on Non-small Cell Lung Cancer: A Meta-analysis

Zhongliu Fangzhi Yanjiu, 2021
Objective To investigate the relation between TMB and the efficiency of PD-1/PD-L1 inhibitors treatment for non-small-cell lung cancer. Methods Studies were searched from PubMed, Embase, Cochrane Library database, Chinese Biomedical Literature Database ...
SHEN Shijun, WANG Qiaoli, YANG Jinjiang, LI Guojian, LI Mengli, ZHANG Xiaoli, GAN Ping   +6 more
doaj   +1 more source