Small and large intestine express a truncated Dab1 isoform that assembles in cell-cell junctions and co-localizes with proteins involved in endocytosis [PDF]
, 2018 Disabled-1 (Dab1) is an essential intracellular adaptor protein in the reelin pathway. Our previous studies in mice intestine showed that Dab1 transmits the reelin signal to cytosolic signalling pathways.
Balda, María S. +5 more
core +1 more source
Residual cancer is a strong predictor of survival in T3 incidental gallbladder cancer
BMC Surgery, 2022 Background and purpose Index cholecystectomy is insufficient for curing T3 incidental gallbladder cancer (IGC), and once residual cancer (RC) is found, the prognosis is often poor.
Chuan You +5 more
doaj +1 more source
Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine [PDF]
, 2019 Background: The upper gastrointestinal tract plays a prominent role in human physiology as the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug uptake.
Bogatyrev, Said R. +2 more
core +1 more source
Regulation of bicarbonate secretion in marine fish intestine by the calcium-sensing receptor [PDF]
, 2018 In marine fish, high epithelial intestinal HCO3- secretion generates luminal carbonate precipitates of divalent cations that play a key role in water and ion homeostasis.
Fuentes, Juan, Gregorio, Silvia
core +2 more sources
The digestion of yeast cell wall polysaccharides in veal calves [PDF]
, 1976 1. The digestibility of the cell wall polysaccharides of an alkane-grown yeast in different parts of the digestive tract of two veal calves fitted with re-entrant cannulas at the end of the ileum was studied by replacing part of the skim-milk powder of ...
Gaillard, B.D.E., Weerden, E.J., van
core +2 more sources
Technology in Cancer Research & Treatment, 2021 Emerging evidence has shown that circular RNAs (circRNAs) serve as a promising biomarker in different malignancies. Specifically, circ_001569 has been found to be upregulated in some types of human gastrointestinal cancer.
Xianbo Shen MM +5 more
doaj +1 more source
E-cadherin can limit the transforming properties of activating β-catenin mutations [PDF]
, 2015 Wnt pathway deregulation is a common characteristic of many cancers. But only Colorectal Cancer predominantly harbours mutations in APC, whereas other cancer types (hepatocellular carcinoma, solid pseudopapillary tumours of pancreas) have activating ...
Alan R Clarke +27 more
core +2 more sources
Caspase-8 controls the gut response to microbial challenges by Tnf-alpha-dependent and independent pathways [PDF]
, 2014 Objectives: Intestinal epithelial cells (IEC) express toll-like receptors (TLR) that facilitate microbial recognition. Stimulation of TLR ligands induces a transient increase in epithelial cell shedding, a mechanism that serves the antibacterial and ...
Basic, Marijana +12 more
core +3 more sources
Frontiers in OncologyPrimary tracheal carcinoma is a rare malignant tumor; its optimal treatment strategy is not yet formally proven. Surgery, especially complete surgical excision, is often considered as the first-line treatment, and chemotherapy has been reported ...
Xiaojing Chang +7 more
doaj +1 more source
Tectorigenin inhibits Caco-2 human colon cells via NF-κB pathway suppression
Bangladesh Journal of Pharmacology, 2015 Effective immunomodulator and pro-inflammatory cytokine, Tumor necrosis factor-α (TNF-α) are considered to be responsible for connecting autoimmune pathological process and contagious diseases.
Xiao-Yu Dai +8 more
doaj +1 more source