Results 71 to 80 of about 685,570 (303)
(Na+ + K+)-ATPase and plasma membrane polarity of intestinal epithelial cells : presence of a brush border antigen in the distal large intestine that is immunologically related to beta subunit [PDF]
, 1989 The previously produced monoclonal antibody IEC 1/48 against cultured rat intestinal crypt cells (Quaroni, A., and K. J. Isselbacher. 1981. J. Natl. Cancer Inst.
Quaroni, A. +9 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Tolvaptan Improves Refractory Ascites and Overall Survival in Cirrhosis: A Meta-Analysis
Current Internal Medicine Research and Practice Surabaya JournalIntroduction: Refractory ascites is a frequent complication associated with liver cirrhosis. Tolvaptan, a V2-receptor antagonist, has shown effectiveness in improving refractory ascites.
Chetan Kalal +3 more
doaj +1 more source
Contemporary diagnostic imaging of diseases of the small intestine – magnetic resonance enteroclysis and enterography [PDF]
, 2019 Examination of intestines using methods of magnetic resonance (MR) enterography and MR enteroclysis is currently considered to be the best way to visualise diseases of the small intestine like Crohn’s disease, other inflammatory diseases of the small ...
Dobrowolska-Bąk, Małgorzata +7 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyIntroductionCrohn’s disease (CD) is a chronic inflammatory bowel disease, of which the etiology involves genetic, environmental and microbial factors.
Alison Da Silva +7 more
doaj +1 more source
Acquired acrodermatitis enteropathica after abdominal surgery: Case report
Case Reports, 2019 Introduction: The treatment of acquired acrodermatitis enteropathica involves zinc supplementation; however, further research is required to establsih the optimal dose and duration of the supplementation.
Adriana Giraldo-Villa +1 more
doaj +1 more source