Objective To estimate the effect of time from symptom onset to start of biologic treatment on achieving inactive arthritis within six months in a cohort of patients with juvenile idiopathic arthritis (JIA). Methods The international UCAN CAN‐DU study prospectively enrolled patients with JIA across Canada and the Netherlands.
Jelleke B. de Jonge +102 more
wiley +1 more source
Multiple intra-articular injections with adipose-derived stem cells for knee osteoarthritis cause severe arthritis with anti-histone H2B antibody production. [PDF]
Hosono Y +6 more
europepmc +1 more source
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu +9 more
wiley +1 more source
Intra-articular Injections of Allogeneic Platelet-Rich Plasma from Responder Patients for the Treatment of Knee Osteoarthritis: A Pilot and Feasibility Clinical Trial. [PDF]
Sánchez M +13 more
europepmc +1 more source
Arthroscopy Association of Canada Position Statement on Intra-articular Injections for Hip Osteoarthritis. [PDF]
Degen RM +17 more
europepmc +1 more source
Intra‐articular and periarticular administrations of betamethasone and triamcinolone acetonide produce systemic effects, with compound‐ and route‐dependent profiles. The results support the MRLs in urine established by WADA and recommend increasing the washout period for betamethasone.
Sergi Coll +8 more
wiley +1 more source
Multiple Intra-Articular Injections of Adipose-Derived Mesenchymal Stem Cells for Canine Osteoarthritis Treatment. [PDF]
Li X, Jian X, Yan Z, Liu H, Zhang L.
europepmc +1 more source
Short-term results of intra-articular injections of stromal vascular fraction for early knee osteoarthritis. [PDF]
Aletto C +5 more
europepmc +1 more source
The IL‐6/STAT3 axis is crucial in rheumatoid arthritis (RA) via Th17 differentiation. The IL‐6/STAT3 signaling pathway is downregulated as a result of the inhibition of IL‐6 and IL‐6R binding by NHA and NAD. NHA and NAD decrease the Th17 differentiation, which lessens the severity of CIA.
Hyung Jin Lim +10 more
wiley +1 more source
Dual intra-articular injections of corticosteroid and hyaluronic acid versus single corticosteroid injection for ankle osteoarthritis: a randomized comparative trial. [PDF]
Woo I, Park JJ, Park CH.
europepmc +1 more source

