Exosomes (small extracellular vesicles) are nanosized vesicles produced naturally by living cells. They can be engineered by various techniques to deliver biologically active molecules to injury sites in atherosclerosis and atherothrombosis. Therefore, an exosome‐based multifunctional nanomedicine for the diagnosis, monitoring, and treatment of these ...
Tuan Huu Nguyen +4 more
wiley +1 more source
Intra-articular Injections of CXCR4-Overexpressing Human Cartilage-Derived Progenitor Cells Improve Meniscus Healing and Protect Against Posttraumatic Osteoarthritis in Immunocompetent Rabbits. [PDF]
Trivedi J +4 more
europepmc +1 more source
Assessment of Blood Profiles and Pain in Sport Horses Undergoing Intrarectal Ozone Therapy
Ozone therapy influenced haemoglobin, MCHC, and AST activity in horses, with transient red blood cell deformities and increased pain scores observed. No clinical symptoms or liver damage occurred. Findings suggest that lower ozone concentrations may reduce treatment‐related discomfort while maintaining therapeutic effects.
Thamirys Dias de Luna Paiva +5 more
wiley +1 more source
Efficacy and Safety of Platelet-Rich Plasma (PRP) Intra-articular Injections in Hip Osteoarthritis: A Systematic Review of Randomized Clinical Trials. [PDF]
Almutairi AN, Alazzeh MS.
europepmc +1 more source
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik +2 more
wiley +1 more source
Intra-articular injections with Carboxymethyl-Chitosan in patients affected by knee osteoarthritis non-responders to hyaluronic acid: a pilot study. [PDF]
Manocchio N +5 more
europepmc +1 more source
ALDH2 Mediated Ferroptosis Regulation in Ischemia–Reperfusion Injury
ABSTRACT Ischemia–reperfusion injury (IRI) is a common complication in diverse clinical settings, including myocardial infarction, stroke, organ transplantation and major surgery. Its pathological core lies in the metabolic disruption caused by blood flow cessation, followed by oxidative stress, inflammatory cascades and cell death upon reperfusion ...
Liang Han, Wen Zhai
wiley +1 more source
Attenuating Cartilage Degeneration in a Low Mechanical Compression Rat Model Through Intra-Articular Injections of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells. [PDF]
Tai C +4 more
europepmc +1 more source
ABSTRACT The objective of this study was to determine and compare the pharmacokinetics of oral firocoxib, oral meloxicam, and transdermal flunixin (TD) in 44 adult, male castrated, crossbred goats. Pharmacokinetic (PK) analysis was performed for each goat in each phase using non‐compartmental methods with descriptive statistics reported.
Mikaela M. Weeder +11 more
wiley +1 more source
Biocompatible Solutions: Evaluating the Safety of Repeated Intra-Articular Injections of pMPCylated Liposomes for Knee Osteoarthritis Therapy in Rat Models. [PDF]
Ramot Y +6 more
europepmc +1 more source

