Results 21 to 30 of about 801,934 (258)

Treating Systematic Errors in Multiple Sclerosis Data [PDF]

, 2005
Multiple sclerosis (MS) is characterized by high variability between patients and, more importantly here, within an individual over time. This makes categorization and prognosis difficult.
Confavreux, C., Daumer, Martin, Ebers, G. C., Heigenhauser, L., Kappos, L., Lederer, C., Neiß, A., Polman, C., Vukusic, S.   +8 more
core   +1 more source

Intra-individual variation in children\u27s physical activity patterns: Implications for measurement [PDF]

, 2009
Children\u27s physical activity (PA) patterns change form day to day. This intra-individual variability affects precision when measuring key physical activity and sedentary behavior variables.
Hands, Beth P, Larkin, Dawne, Olds, Tim, Parker, Helen, Ridley, Kate   +4 more
core   +1 more source

Development of a Sandwich ELISA to Measure Exposure to Occupational Cow Hair Allergens [PDF]

, 2011
Background: Cow hair and dander are important inducers of occupational allergies in cattle-exposed farmers. To estimate allergen exposure in farming environments, a sensitive enzyme immunoassay was developed to measure cow hair allergens.
Angelika Flagge, Anne Spickenheuer, Berger I, Christina Fleischer, Dennis Nowak, Eva Zahradnik, Ferrer A, Heutelbeck AR, Hinze S, Hinze S, Ilka Noss, Ingrid Sander, Joachim Sültz, Krakowiak A, Krop EJ, Lydia Bruckmaier, Monika Raulf-Heimsoth, Noss I, Noss I, Prahl P, Prahl P, Prahl P, Radon K, Rautiainen J, Rautiainen J, Renstrom A, Restani P, Rudolf Schierl, Saarelainen S, Thomas Brüning, Virtanen T, Virtanen T, Virtanen T, Ylonen J, Ylonen J, Ylonen J, Zahradnik E   +36 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Intra- and inter-individual variation in self-reported code-switching patterns of adult multilinguals [PDF]

, 2014
The present study is a large-scale quantitative analysis of intra-individual variation (linked to type of interlocutor) and inter-individual variation (linked to multilingualism, sociobiographical variables and three personality traits) in self-reported ...
Dewaele, Jean-marc, Li, Wei, Wei, Li
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Two Distinct, Geographically Overlapping Lineages of the Corallimorpharian Ricordea Florida (Cnidaria: Hexacorallia: Ricordeidae) [PDF]

, 2011
We examined the genetic variation of the corallimorpharian Ricordea florida; it is distributed throughout the Caribbean region and is heavily harvested for the marine aquarium trade. Eighty-four distinct individuals of R. florida were sequenced from four
Lado-Insua, T., Rhyne, Andrew L., Rodríguez-Matos, L., Schizas, N. V., Torres-Pratts, H.   +4 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Intra-individual variation in resting metabolic rate during the menstrual cycle [PDF]

British Journal of Nutrition, 2003
Little information exists on the extent of day-to-day intra-individual variation in resting metabolic rate (RMR) in women. The present study has investigated the intra-individual variation in RMR of women during the menstrual cycle. Nineteen women (naturally cycling non-pill users) were recruited to the study.
Henry, C, Lightowler, H, Marchini, J
openaire   +3 more sources