Results 41 to 50 of about 7,284,729 (277)

Intra-individual coefficients of variation by number of samples and by collection time (median (25^th– 75^th percentile).

, 2018
Intra-individual coefficients of variation by number of samples and by collection time (median (25th– 75th percentile).
Sophie Marielle van den Belt (5434844), Dick de Zeeuw (80605), Valentina Gracchi (5434847), Hiddo Jan Lambers Heerspink (5434850)   +3 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Average of the intra-individual coefficients of variation (CV): Standard deviations are given within parenthesis.

, 2020
Average of the intra-individual coefficients of variation (CV): Standard deviations are given within parenthesis.
Jeong-Lim Kim (6058424), Marianne Andersson (8356647), Gunilla Runström Eden (8356650), Björn Bake (836612), Spela Kokelj (8356644), Anna-Carin Olin (168124)   +5 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Longitudinal variability of time-location/activity patterns of population at different ages: a longitudinal study in California

Environmental Health, 2011
Background Longitudinal time-activity data are important for exposure modeling, since the extent to which short-term time-activity data represent long-term activity patterns is not well understood.
Cassady Diana L, Lee Kiyoung, Bennett Deborah H, Wu Xiangmei, Ritz Beate, Hertz-Picciotto Irva   +5 more
doaj   +1 more source

Microplastic exposure increases predictability of predator avoidance strategies in hermit crabs

Journal of Hazardous Materials Letters, 2020
The contamination of natural systems with plastic debris has become one of the most pressing global environmental issues. Microplastics (MPs) are of particular concern because their ubiquity and small size make them available for ingestion by a range of ...
Gerrit B. Nanninga, Cat Horswill, Sarah M. Lane, Andrea Manica, Mark Briffa   +4 more
doaj   +1 more source

Linguistic, social, and individual factors constraining variation in spoken Swiss Standard German [PDF]

, 2021
This chapter explores linguistic, social, and individual factors constraining spoken Swiss Standard German. The empirical focus of this study is on the variables (k) and (ç), which are well-attested to vary both at the level of the Swiss German speech ...
Bülow, Lars, Andrin Büchler, Nicolai Rawyler, Britain, David, Büchler, Andrin, David Britain, Rawyler, Nicolai, Schneider, Christa, Christa Schneider, Lars Bülow   +9 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Reconciling Inter- and Intra-Individual Variation in L2 Socio-Pragmatic Development: Intensifier Variation in Spoken German

Languages
This study is the first to scrutinize the rates of, and the lexical diversity in, adjective intensification in second language (L2) German. We additionally attend to the issue concerning whether sociodemographic variables (i.e., length of residence, age,
Mason A. Wirtz
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source