Maternal urinary metabolic signatures of fetal growth and associated clinical and environmental factors in the INMA study [PDF]
, 2016 Background Maternal metabolism during pregnancy is a major determinant of the intra-uterine environment and fetal outcomes. Herein, we characterize the maternal urinary metabolome throughout pregnancy to identify maternal metabolic signatures of fetal ...
Coen, M +8 more
core +6 more sources
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT. [PDF]
, 2015 OBJECTIVES: To determine inter-session and intra/inter-individual variations of the attenuations of aortic blood/myocardium with MDCT in the context of calcium scoring.
Dehmeshki, J. +3 more
core +3 more sources
Multidimensionality and intra-individual variation in host manipulation by an acanthocephalan [PDF]
Parasitology, 2008 SUMMARYTrophically-transmitted parasites frequently alter multiple aspects of their host's phenotype. Correlations between modified characteristics may suggest how different traits are mechanistically related, but these potential relationships remain unexplored.
BENESH, D.P. +2 more
openaire +5 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah +7 more
wiley +1 more source
La variation inter-individuelle et intra-individuelle dans le parler occitan de Sénaillac-Lauzès (Lot, France) [PDF]
, 2012 International audienceBased on a series of phonological, morphological and syntactic examples all collected in a village in Southern France, this paper will examine inter and intraindividual variation in an Occitan vernacular dialect.
Sibille, Jean
core +1 more source
Comparison of intra-individual coefficients of variation on the paired sampling data when inter-individual variations are different between measures [PDF]
, 2016 Additional file 2. Supplemental figures for the pain intensity data (residual plots, PâP plots and Cookâs distance against leverage/(1-leverage))
Fumiaki Kiyomi +3 more
core +2 more sources
Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew +11 more
wiley +1 more source
Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome
, 2019 Mitochondrial DNA (mtDNA) heteroplasmy (intra-individual variation) varies among different human tissues and increases with age, suggesting that the majority of mtDNA heteroplasmies are acquired, rather than inherited.
Eis-Hübinger, A. +6 more
core +1 more source
Evaluation of Generic Drugs Using Intra-Individual Variation Index
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 2006 We previously reported that the protocols of bioequivalence studies on generic pravastatin sodium had not been standardized. The bioequivalence of generic drugs is confirmed by crossover studies using healthy volunteers. In this study, we examined protocols for bioequivalence studies on generic itraconazole (ITCZ) formulations which show poor ...
Kyohei Watanabe +5 more
openaire +2 more sources