Results 161 to 170 of about 2,992,178 (408)
Poly I:C Delivery into J774.1 & RAW264.7 Macrophages Induces Rapid Cell Death [PDF]
Background: Cytosolic double-stranded RNA (dsRNA) is an important ‘molecular signature’ for the detection of intracellular viral infections. Although intracellular dsRNA is a known potent inducer of apoptosis, the optimal time and dose for the onset of ...
Cheah Wen Yapp+2 more
doaj
The activation of the ventral tegmental area (VTA) can rebuild the tonotopic representation in the primary auditory cortex (A1), but the cellular mechanisms remain largely unknown. Here, we investigated the firing patterns and membrane potential dynamics
Yunxiao eLou+6 more
doaj +1 more source
Tuning the kinetics of intracellular transport [PDF]
A variety of complex mechanisms, from chemical reaction pathways to active fluctuations, orchestrate molecular transport in intracellular environments. Despite significant recent progress in visualizing and probing these processes, little is known about how tunable the resulting dynamics is through external physical controllers.
arxiv
Intracellular Amounts of Nucleic Acids and Protein During Pollen Grain Growth in Tradescantia [PDF]
John Woodard
openalex +1 more source
Intracellular Communication [PDF]
Grimm, Bernhard+3 more
openaire +2 more sources
Definition of intracellular pathogens [PDF]
Most microorganisms are destroyed by the host tissues through processes which usually involve phagocytosis and lysosomal disruption. However, some organisms are capable of growing inside macrophages and avoiding destruction. This paper describes the normal phagocytic process and how it is avoided by certain viruses, bacteria and protozoa, and the ...
openaire +3 more sources
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh+5 more
wiley +1 more source
Cryoloading: Introducing Large Molecules into Live Synaptosomes
Neurons communicate with their target cells primarily by the release of chemical transmitters from presynaptic nerve terminals. The study of CNS presynaptic nerve terminals, isolated as synaptosomes (SSMs) has, however, been hampered by the typical ...
Arup R Nath+2 more
doaj +1 more source
Apoptosis and necrosis are considered conceptually and morphologically distinct forms of cell death. Here, we report that demise of human T cells caused by two classic apoptotic triggers (staurosporin and CD95 stimulation) changed from apoptosis to ...
M. Leist+4 more
semanticscholar +1 more source