Results 171 to 180 of about 2,142,587 (349)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Exogenous indole promotes florfenicol tolerance in <i>Edwardsiella tarda</i>. [PDF]

open access: yesVirulence
Zheng Y   +8 more
europepmc   +1 more source

Isolation ofWaddlia malaysiensis, A Novel Intracellular Bacterium, from Fruit Bat (Eonycteris spelaea) [PDF]

open access: diamond, 2005
Paul K.B. Chua   +5 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Acid-sensing ion channel 1a contributes to the calcium/calmodulin-dependent ferroptosis and aggravates intervertebral disc degeneration. [PDF]

open access: yesRedox Rep
Zhou LP   +9 more
europepmc   +1 more source

IFI16 is an innate immune sensor for intracellular DNA

open access: yesNature Immunology, 2010
Leonie Unterholzner   +14 more
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Correction: Remodeling tumor microenvironment using prodrug nMOFs for synergistic cancer therapy. [PDF]

open access: yesJ Nanobiotechnology
Dong J   +9 more
europepmc   +1 more source

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