Results 201 to 210 of about 3,033,431 (331)

Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?

Advanced Biology, EarlyView.
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez, Hao Zhang, Dhananjay Sah, Juan P. Cata   +3 more
wiley   +1 more source

Endogenous hepcidin plays an essential role in <i>Mycobacterium tuberculosis</i> Rv1876 antigen-induced antimicrobial activity in macrophages. [PDF]

Emerg Microbes Infect
Park HS, Choi HG, Jang IT, Pham TA, Jiang Z, Son YJ, Kim K, Kim HJ.   +7 more
europepmc   +1 more source

CHARACTERIZATION OF INTRACELLULAR, GLUCOSIDIC POLYSACCHARIDE PRODUCED BY BRUCELLA SUIS [PDF]

, 1958
N. D. Gary, L. L. Kupferberg, L. Gráf
openalex   +1 more source

Pyroptotic cell death defends against intracellular pathogens

Immunological Reviews, 2015
Ine Jorgensen, Edward A. Miao
semanticscholar   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Identification of the Francisella novicida FTN_0096 as a factor involved in intracellular replication and host response. [PDF]

PLoS One
Wardhana DK, Shimizu T, Watanabe K, Uda A, Watarai M.   +4 more
europepmc   +1 more source

The Rôle of Intracellular Cations on Liver Glycogen Formation in Vitro

, 1942
A. Baird Hastings, John M. Buchanan
openalex   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

Phage-mediated TLR2 signaling attenuates intracellular Mycobacterium abscessus survival in macrophages. [PDF]

Sci Rep
Kapoor H, Maves AM, Bowder MA, Danelishvili L.   +3 more
europepmc   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

Advanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams, Ana I Borrachero‐Conejo, Pratheepa Kumari Rasiah, Emanuella Saracino, Roberto Zamboni, Eric Duco Jansen, Valentina Benfenati, Anita Mahadevan‐Jansen   +7 more
wiley   +1 more source