Results 281 to 290 of about 2,142,587 (349)

Receptor-Mediated Shuttling of a D-Amino Acid Peptide Achieves High Nanomolar Cytosolic Concentrations. [PDF]

J Am Chem Soc
List M, Beck-Sickinger AG.
europepmc   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Fluorous oligoarginines as supra-enhancers for intracellular and transdermal peptide delivery. [PDF]

Bioact Mater
Rong G, Fan Q, Chen K, Cheng Y, Hu J.
europepmc   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

SLC16A3 in lung adenocarcinoma regulates glycolysis and lactate release to facilitate M2 polarization of tumor-associated macrophages : Short Title: SLC16A3 reinforces macrophage M2 polarization through glycolysis. [PDF]

Cancer Immunol Immunother
Chen P, Qing Q, Gao H, Qin Z, Lv J.
europepmc   +1 more source

Branching, crosslinking, and decentralization of microtubules accelerates intracellular assembly

Apurba Sarkar, Alex Mogilner, Raja Paul
openalex   +2 more sources

Transcriptional regulation of the GTP cyclohydrolase I gene via the NF-κB pathway by bacterial and viral immune stimulants. [PDF]

J Biochem
Ozawa M, Hara S, Sakamoto M, Suzuki T, Niiyama S, Kakihana Y, Ichinose H.   +6 more
europepmc   +1 more source

Intracellular colloidal salts

The Journal of Physiology, 1906
openaire   +3 more sources

The role of the TIM-3 receptor in inflammatory bowel disease and autoimmunity: implications for TIM-3 and TCR crosstalk. [PDF]

J Mol Med (Berl)
Gabel M, Knauss A, Neurath MF, Weigmann B.   +3 more
europepmc   +1 more source

Cucurbitacin D Induces Apoptotic Cell Death via NOX4 and Overcomes Radioresistance in Colorectal Cancer. [PDF]

Int J Mol Sci
Kim TW.
europepmc   +1 more source