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Intracellular markers

Journal of Immunological Methods, 2000
An increased level of complexity will be encountered when developing protocols for intracellular markers. Protocols for surface markers have been successfully standardized, however it is understood that no single method is appropriate for all intracellular staining.
S K, Koester, W E, Bolton
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Intracellular organisms

International Journal of Antimicrobial Agents, 1997
The intracellular location of some microorganisms allow them to resist antibiotics with poor ability to penetrate eukaryotic cell membranes, such as the beta-lactam compounds. Pharmacokinetic and pharmacodynamic properties of antibiotics within eukaryotic cells have been defined in the last two decades.
M, Maurin, D, Raoult
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Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine.

Advanced Drug Delivery Reviews, 2019
Nanoparticle-based therapeutics and diagnostics are commonly referred to as nanomedicine and may significantly impact the future of healthcare. However, the clinical translation of these technologies is challenging.
Nathan D. Donahue   +2 more
semanticscholar   +1 more source

Intracellular Life

Critical Reviews in Microbiology, 1999
Intracellular parasites and endosymbionts are present in almost all forms of life, including bacteria. Some eukaryotic organelles are believed to be derived from ancestral endosymbionts. Parasites and symbionts show several adaptations to intracellular life.
D, Corsaro   +3 more
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Intracellular Cholesterol Trafficking

Cold Spring Harbor Perspectives in Biology, 2023
Cholesterol is an essential lipid species of mammalian cells. Cells acquire it through synthesis in the endoplasmic reticulum (ER) and uptake from lipoprotein particles. Newly synthesized cholesterol is efficiently distributed from the ER to other organelles via lipid-binding/transfer proteins concentrated at membrane contact sites (MCSs) to reach the ...
Ikonen Elina, Olkkonen Vesa M.
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Intracellular channels

Current Opinion in Neurobiology, 1994
Intracellular channels are located on the membranes of intracellular organelles and are involved in ion transfer, within the cytosolic compartments, in response to internal stimuli. Recently, various types of inositol 1,4,5-trisphosphate- and ryanodine-sensitive Ca(2+)-release channels, mitochondrial voltage-dependent anion channels, and a vesicular Cl-
T, Furuichi   +3 more
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Intracellular Cytokines

Current Protocols in Cytometry, 2004
AbstractThe principal technique described in this unit was developed for detecting cytokines produced by T cells, specifically interferon gamma (IFN‐γ) and interleukin 4 (IL‐4). In addition to providing information about which cytokines are being produced, it also helps to phenotypically identify the specific cells producing them.
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Intracellular proteolysis

Trends in Genetics, 1999
Our present understanding of intracellular protein degradation developed from an attempt to understand the metabolic stability of proteins in cells. With the unravelling of its complex biochemical machinery has come a realization that protein degradation plays an important role in the most crucial events in the cell cycle, in signal transduction and in
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Intracellular buffering

Respiration Physiology, 1978
In the quantification of buffering the distinct roles of bicarbonate and of other buffers must be taken into account. The determination of the total non-bicarbonate buffer value, betaa, in intact tissues is complicated by active pH regulation and by heterogeneity of cytoplasm with respect to betaa, while heterogeneity with respect to pH in vivo could ...
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Intracellular Edema

2017
The macula is predisposed to edema in various retinal conditions, even when the insult is remote from the macula. The various factors that may predispose the macula to edema include high metabolic activity, radial arrangement of the Henle's layer, lack of inner layers at the fovea, and lack of blood supply at the fovea.
Raja, Narayanan, Baruch D, Kuppermann
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