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Intracellular membrane morphology
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1995The membrane-bound organelles on the exocytic and endocytic pathways are linked by vesicles which bud from one membrane compartment, carrying selected cargo, and fuse with the next on the pathway. The principles underlying this vesicle-mediated traffic go a long way towards explaining the morphology of these intracellular organelles and their behaviour
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Effect of taurine on a muscle intracellular membrane
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1973Abstract Sarcoplasmic reticulum from rat skeletal muscle had rates of calcium oxalate uptake dependent upon the speed with which the muscle was removed and homogenized. Rapidly isolated sarcoplasmic reticulum (muscle removed and homogenized within 20 min) showed a 25% increase in rate of calcium oxlate uptake in the presence of 15 mM taurine, and the
Rubin Bressler, Ryan J. Huxtable
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The Network of Intracellular Membranes
Hospital Practice, 1973If the external membrane organizes the cell as a unit, the internal membranes make possible the differentiation of activities within the cell, greatly increasing its working surface. An overview of the membranes that define the organelles within the cell sap notes they are structurally of two types, relates structure to function, and describes the ...
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Intracellular ATP and Cardiac Membrane Currents [PDF]
, 1988 Energy metabolism has a strong influence on the electrical activities of cardiac muscle (Trautwein et al., 1954; De Mello, 1959; MacLeod and Daniel, 1965; for review see Carmeliet, 1978). When cardiac muscle is exposed to anoxic conditions or metabolic inhibitors, or is depleted of substrates, the plateau of the action potential is depressed in the ...
Tohru Shibasaki, A Noma
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Genetic Defects of Intracellular-Membrane Transport
New England Journal of Medicine, 2000The compartmentalization of functions into distinct membrane-bound organelles is a central characteristic of cells. The protein and lipid composition of these organelles is unique, a factor that is vital for their proper function. This necessitates tightly controlled transport of biomolecules from their sites of synthesis or uptake to specific ...
Elina Ikonen, Vesa M. Olkkonen
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Enzymology of intracellular membrane fusion
Klinische Wochenschrift, 1991A combination of cell-free biochemical and morphological studies has revealed that a coated bud-coated vesicle transport system shuttles newly synthesized proteins through the successive processing compartments of the Golgi apparatus. These "Golgi coated vesicles" operate in a manner formally analogous to the clathrin coated pit-coated vesicle system ...
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5 Intracellular membrane fusion
1994The NSF, SNAP, and SNAP receptors are key elements of the intracellular membrane fusion machinery. We use an affinity purification scheme, based on the function of SNAP receptor in assembling 20S fusion particles from NSF and SNAP proteins, to purify SNAP receptors from brain.
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2009
Fusion of biological membranes plays an important role in cell structure and function. It is essential for organelle biogenesis, vesicle targeting, constitutive and regulated exocytosis, endocytosis, pathogen invasion of host cells, sperm-egg fusion and skeletal muscle formation.
Dalu Xu, Jesse C. Hay
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Fusion of biological membranes plays an important role in cell structure and function. It is essential for organelle biogenesis, vesicle targeting, constitutive and regulated exocytosis, endocytosis, pathogen invasion of host cells, sperm-egg fusion and skeletal muscle formation.
Dalu Xu, Jesse C. Hay
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Intracellular Parcel Service: Current Issues in Intracellular Membrane Trafficking
2014Eukaryotic cells contain a multitude of membrane structures that are connected through a highly dynamic and complex exchange of their constituents. The vibrant instability of these structures challenges the classical view of defined, static compartments that are connected by different types of vesicles. Despite this astonishing complexity, proteins and
Herrmann, J. M., Spang, A.
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Functional architecture of an intracellular membrane t-SNARE
Nature, 2000Lipid bilayer fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, of which one is supplied by the v-SNARE and the other three by the t-SNARE.
Walter Nickel +11 more
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