Results 1 to 10 of about 85,181 (295)

Ubiquitin-mediated degradation at the Golgi apparatus [PDF]

Frontiers in Molecular Biosciences, 2023
The Golgi apparatus is an essential organelle of the secretory pathway in eukaryotic cells. It processes secretory and transmembrane proteins and orchestrates their transport to other endomembrane compartments or the plasma membrane.
Lana Buzuk, Doris Hellerschmied
doaj   +4 more sources

The effects of WWP1 overexpression on the golgi apparatus stress response and proteoglycan production in adipocytes [PDF]

Scientific Reports
White adipocytes are a major component of white adipose tissue (WAT) and help to maintain systemic metabolic homeostasis by storing energy and secreting adipokines. In mice deficient in the protein WWP1 (WW domain-containing E3 ubiquitin protein ligase 1)
Yuka Nozaki, Fumika Suwa, Kazuhiro Furuya, Masahiro Komeno, Shunsuke Hoshino, Yuhei Mizunoe, Kyohei Higashi, Masaki Kobayashi, Yoshikazu Higami   +8 more
doaj   +2 more sources

Characterization of the glutathione redox state in the Golgi apparatus [PDF]

Redox Biology
Redox homeostasis is crucial for cell function, and, in eukaryotic cells, studying it in a compartmentalized way is essential due to the redox variations between different organelles.
Carla Miró-Vinyals, Sarah Emmert, Gina Grammbitter, Alex Jud, Tobias Kockmann, Pablo Rivera-Fuentes   +5 more
doaj   +3 more sources

MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migratio [PDF]

eLife
The reorientation of the Golgi apparatus is crucial for cell migration and is regulated by multipolarity signals. A number of non-centrosomal microtubules anchor at the surface of the Golgi apparatus and play a vital role in the Golgi reorientation, but ...
Peipei Xu, Rui Zhang, Zhengrong Zhou, Honglin Xu, Yuejia Li, Mengge Yang, Ruifan Lin, Yingchun Wang, Xiahe Huang, Qi Xie, Wenxiang Meng   +10 more
doaj   +2 more sources

A Golgi apparatus‑related subtype and risk signature predicts prognosis and evaluates immunotherapy response in gastric cancer [PDF]

Discover Oncology
Background Gastric cancer (GC) remains a significant health burden, calling for the discovery of novel biomarkers. Golgi apparatus, a crucial cellular organelle involved in tumorigenesis, remains underexplored in GC research.
Ruyue Chen, Zengwu Yao, Lixin Jiang, Jinchen Hu   +3 more
doaj   +2 more sources

Biogenesis of specialized lysosomes in differentiated keratinocytes relies on close apposition with the Golgi apparatus [PDF]

Cell Death and Disease
Intracellular organelles support cellular physiology in diverse conditions. In the skin, epidermal keratinocytes undergo differentiation with gradual changes in cellular physiology, accompanying remodeling of lysosomes and the Golgi apparatus.
Sarmistha Mahanty, Ptissam Bergam, Vivek Belapurkar, Litralson Eluvathingal, Nikita Gupta, Bruno Goud, Deepak Nair, Graça Raposo, Subba Rao Gangi Setty   +8 more
doaj   +2 more sources

Mechanistic insights into cargo sorting and export from the Golgi apparatus [PDF]

Nature Reviews Molecular Cell Biology
Emma T Watson, Julia Von Blume, Von Blume Julia   +2 more
exaly   +2 more sources

H5 subtype avian influenza virus induces Golgi apparatus stress response via TFE3 pathway to promote virus replication. [PDF]

PLoS Pathogens
During infection, avian influenza virus (AIV) triggers endoplasmic reticulum (ER) stress, a well-established phenomenon in previous research. The Golgi apparatus, situated downstream of the ER and crucial for protein trafficking, may be impacted by AIV ...
Yuncong Yin, Xianjin Kan, Xinyu Miao, Yingjie Sun, Sujuan Chen, Tao Qin, Chan Ding, Daxin Peng, Xiufan Liu   +8 more
doaj   +2 more sources

The Preparation of Golgi Apparatus-Targeted Polymer Dots Encapsulated with Carbon Nanodots of Bright Near-Infrared Fluorescence for Long-Term Bioimaging

Molecules, 2023
As a vital organelle in eukaryotic cells, the Golgi apparatus is responsible for processing and transporting proteins in cells. Precisely monitoring the status of the Golgi apparatus with targeted fluorescence imaging technology is of enormous importance
Yiping Lu, Wei Song, Zhiquan Tang, Wenru Shi, Shumei Gao, Jun Wu, Yuan Wang, Hu Pan, Yangang Wang, Hong Huang   +9 more
doaj   +1 more source

Maintaining Golgi Homeostasis: A Balancing Act of Two Proteolytic Pathways

Cells, 2022
The Golgi apparatus is a central hub for cellular protein trafficking and signaling. Golgi structure and function is tightly coupled and undergoes dynamic changes in health and disease.
Ron Benyair, Avital Eisenberg-Lerner, Yifat Merbl   +2 more
doaj   +1 more source