Decoupling polarization of the Golgi apparatus and GM1 in the plasma membrane.
PLoS ONE, 2013 Cell polarization is a process of coordinated cellular rearrangements that prepare the cell for migration. GM1 is synthesized in the Golgi apparatus and localized in membrane microdomains that appear at the leading edge of polarized cells, but the ...
Blaine Bisel +3 more
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Predicting Sub-Golgi Apparatus Resident Protein With Primary Sequence Hybrid Features
IEEE Access, 2020 The Golgi apparatus is a significant membrane-bound organelle of eukaryotic cells that is made up of a series of flattened, stacked pouches (called cisternae).
Chunyu Wang +3 more
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Retro-2 alters Golgi structure
Scientific Reports, 2022 Retro-2 directly interacts with an ER exit site protein, Sec16A, inhibiting ER exit of a Golgi tSNARE, Syntaxin5, which results in rapid re-distribution of Syntaxin5 to the ER. Recently, it was shown that SARS-CoV-2 infection disrupts the Golgi apparatus
Xihua Yue +7 more
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Characterization of lipoprotein particles isolated from the Golgi apparatus of rat liver
Journal of Lipid Research, 1969 It has been proposed that particles within tubules and vesicles of the Golgi apparatus of liver cells are precursors of very low density lipoproteins in blood plasma. To characterize these particles we isolated a cell fraction rich in Golgi apparatus and
Robert W. Mahley +2 more
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The spinal muscular atrophy disease protein SMN is linked to the Golgi network. [PDF]
PLoS ONE, 2012 Proximal spinal muscular atrophy (SMA) is a neurodegenerative disorder caused by deficiency of the ubiquitous Survival of Motor Neuron (SMN) protein. SMN has been shown to be transported in granules along the axon and moved through cytoskeletal elements.
Chen-Hung Ting +5 more
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Positioning the Golgi Apparatus [PDF]
Cell, 2004 Ríos et al. (2004) report in this issue that the Golgi protein GMAP-210 is sufficient to confer pericentrosomal positioning and recruits gamma-tubulin and associated microtubule-nucleating ring complex proteins to Golgi membranes. The results raise the possibility that short microtubules emanate from the Golgi to mediate its organization and ...
openaire +2 more sources
Dissection of the asynchronous transport of intestinal microvillar hydrolases to the cell surface [PDF]
, 1988 Novel subcellular fractionation procedures and pulse-chase techniques were used to study the intracellular transport of the microvillar membrane hydrolases sucrase-isomaltase and dipeptidylpeptidase IV in the differentiated colon adenocarcinoma cell line
B Stieger +11 more
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The ER-Golgi-Intermediate compartment : dynamics and cargo sorting studied by time-lapse video microscopy [PDF]
, 2004 Membrane trafficking in mammalian cells proceeds through several steps including sorting the correct components to be transported, packaging them into appropriate containers and conveying the carriers to the proper organelles with which they fuse.
Ben-Tekaya, Houchaïma
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The Golgi Apparatus: Morphology and Function with Recent Facts
Bezmiâlem Science, 2019 At the center of the secretory pathway, the Golgi complex ensures correct processing and sorting of cargos towards their final destination sites which are the cytoplasm, plasma membrane, and endosome-lysosome system.
Mukaddes Eşrefoğlu
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GO-PROMTO illuminates protein membrane topologies of glycan biosynthetic enzymes in the Golgi apparatus of living tissues. [PDF]
PLoS ONE, 2012 The Golgi apparatus is the main site of glycan biosynthesis in eukaryotes. Better understanding of the membrane topology of the proteins and enzymes involved can impart new mechanistic insights into these processes.
Casper Søgaard +6 more
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