Results 11 to 20 of about 1,085,148 (332)
Angewandte Chemie - International Edition, 2021 Golgi apparatus is emerging as a key signaling hub of cells and an important target for cancer therapy, but there are few approaches for targeting Golgi and selectively killing cancer cells.
Weiyi Tan +5 more
semanticscholar +3 more sources
Immunity, 2021 Activation of the cyclic guanosine monophosphate (GMP)-AMP (cGAMP) sensor STING requires its translocation from the endoplasmic reticulum to the Golgi apparatus and subsequent polymerization.
Run Fang +6 more
semanticscholar +3 more sources
A Golgi apparatus‑related subtype and risk signature predicts prognosis and evaluates immunotherapy response in gastric cancer [PDF]
Discover OncologyBackground Gastric cancer (GC) remains a significant health burden, calling for the discovery of novel biomarkers. Golgi apparatus, a crucial cellular organelle involved in tumorigenesis, remains underexplored in GC research.
Ruyue Chen +3 more
doaj +2 more sources
Biogenesis of specialized lysosomes in differentiated keratinocytes relies on close apposition with the Golgi apparatus [PDF]
Cell Death and DiseaseIntracellular organelles support cellular physiology in diverse conditions. In the skin, epidermal keratinocytes undergo differentiation with gradual changes in cellular physiology, accompanying remodeling of lysosomes and the Golgi apparatus.
Sarmistha Mahanty +8 more
doaj +2 more sources
H5 subtype avian influenza virus induces Golgi apparatus stress response via TFE3 pathway to promote virus replication. [PDF]
PLoS PathogensDuring infection, avian influenza virus (AIV) triggers endoplasmic reticulum (ER) stress, a well-established phenomenon in previous research. The Golgi apparatus, situated downstream of the ER and crucial for protein trafficking, may be impacted by AIV ...
Yuncong Yin +8 more
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Molecules, 2023 As a vital organelle in eukaryotic cells, the Golgi apparatus is responsible for processing and transporting proteins in cells. Precisely monitoring the status of the Golgi apparatus with targeted fluorescence imaging technology is of enormous importance
Yiping Lu +9 more
doaj +1 more source
Maintaining Golgi Homeostasis: A Balancing Act of Two Proteolytic Pathways
Cells, 2022 The Golgi apparatus is a central hub for cellular protein trafficking and signaling. Golgi structure and function is tightly coupled and undergoes dynamic changes in health and disease.
Ron Benyair +2 more
doaj +1 more source
The role of the Golgi apparatus in disease (Review)
International Journal of Molecular Medicine, 2021 The Golgi apparatus is known to underpin many important cellular homeostatic functions, including trafficking, sorting and modifications of proteins or lipids.
Jianyang Liu +5 more
semanticscholar +1 more source
Current Biology, 2000 Farquhar MG, Palade GE: The Golgi apparatus: 100 years of progress and controversy.Trends Cell Biol 1998, 8:2-10.Nelson WJ: W(h)ither the Golgi during mitosis?J Cell Biol 2000, 149:243-248.Palade GE: Intracellular aspects of the process of protein secretion.Science 1975, 189:347-388.Rothman JE, Wieland FT: Protein sorting by transport vesicles.Science ...
Short, Ben, Barr, Francis A.
openaire +2 more sources
The Proteasomal Deubiquitinating Enzyme PSMD14 Regulates Macroautophagy by Controlling Golgi-to-ER Retrograde Transport [PDF]
, 2020 Ubiquitination regulates several biological processes, however the role of specific members of the ubiquitinome on intracellular membrane trafficking is not yet fully understood.
Arias-Muñoz, Eloisa +16 more
core +2 more sources