Golgi-Targeted Fluorescent Probe for Imaging NO in Alzheimer’s Disease
, 2022 Nitric oxide (NO) is a crucial neurotransmitter participating in many biological processes via nitrosylation reaction. NO produced in diverse subcellular regions also regulates the function of cells in different manners.
Ya Liu (205636) +5 more
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Branched Actin Maintains Acetylated Microtubule Network in the Early Secretory Pathway
Cells, 2021 In the early secretory pathway, the delivery of anterograde cargoes from the endoplasmic reticulum (ER) exit sites (ERES) to the Golgi apparatus is a multi-step transport process occurring via the ER-Golgi intermediate compartment (IC, also called ERGIC).
Azumi Yoshimura +3 more
doaj +1 more source
The role of the lectin VIP36 in the early secretory pathway [PDF]
, 2010 Lectins are of emerging importance for quality control and intracellular transport of glycoproteins in mammalian cells. One of the most prominent lectins involved in intracellular transport is ERGIC-53, which belongs to the family of L-type lectins ...
Reiterer, Veronika
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ARF-GAP-mediated interaction between the ER-Golgi v-SNAREs and the COPI coat [PDF]
, 2002 In eukaryotic cells, secretion is achieved by vesicular transport. Fusion of such vesicles with the correct target compartment relies on SNARE proteins on both vesicle (v-SNARE) and the target membranes (t-SNARE).
Rein, U. +15 more
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Cell Communication and Signaling, 2023 Background Lung infections caused by Streptococcus pneumonia are a global leading cause of death. The reactive oxygen species H2O2 is one of the virulence factors of Streptococcus pneumoniae. The Golgi apparatus is essential for the inflammatory response
Björn Klabunde +7 more
doaj +1 more source
Adaptation of the Golgi Apparatus in Cancer Cell Invasion and Metastasis
Frontiers in Cell and Developmental Biology, 2021 The Golgi apparatus plays a central role in normal cell physiology by promoting cell survival, facilitating proliferation, and enabling cell-cell communication and migration.
Sarah Bui +5 more
doaj +1 more source
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]
, 2007 Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Falguières, Thomas +15 more
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Associating bovine herpesvirus 1 envelope glycoprotein gD with activated phospho-PLC-γ1(S1248)
Microbiology Spectrum, 2023 Phospholipase C gamma 1 (PLC-γ1) may locate at distinct subcellular locations, such as cytosol, plasma membrane, and nucleus for varied biological functions.
Chang Liu +8 more
doaj +1 more source
Bridging the gap between glycosylation and vesicle traffic
Frontiers in Cell and Developmental Biology, 2016 Glycosylation is recognised as a vitally important posttranslational modification. The structure of glycans that decorate proteins and lipids is largely dictated by biosynthetic reactions occurring in the Golgi apparatus.
Daniel eUngar, Peter eFisher
doaj +1 more source
"In vitro" reconstitution of "trans"-Golgi exit and the effect of GAG attachment on protein sorting [PDF]
, 2007 The trans-Golgi network is one of the main sorting stations for proteins and lipids in the eukaryotic endomembrane system. Yet, the mechanisms for sorting and transport out of the trans-Golgi network remain poorly understood.
Kobialka, Szymon
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