Golgi-Targeted Fluorescent Probe for Imaging NO in Alzheimer’s Disease
Nitric oxide (NO) is a crucial neurotransmitter participating in many biological processes via nitrosylation reaction. NO produced in diverse subcellular regions also regulates the function of cells in different manners.
Ya Liu (205636) +5 more
core +1 more source
Branched Actin Maintains Acetylated Microtubule Network in the Early Secretory Pathway
In the early secretory pathway, the delivery of anterograde cargoes from the endoplasmic reticulum (ER) exit sites (ERES) to the Golgi apparatus is a multi-step transport process occurring via the ER-Golgi intermediate compartment (IC, also called ERGIC).
Azumi Yoshimura +3 more
doaj +1 more source
Visualization of secretory cargo transport within the Golgi apparatus
To describe trafficking of secretory cargo within the Golgi apparatus, the cisternal maturation model predicts that Golgi cisternae change their properties from cis to trans while cargo remains in the cisternae.
Kazuo Kurokawa +7 more
semanticscholar +1 more source
Background Lung infections caused by Streptococcus pneumonia are a global leading cause of death. The reactive oxygen species H2O2 is one of the virulence factors of Streptococcus pneumoniae. The Golgi apparatus is essential for the inflammatory response
Björn Klabunde +7 more
doaj +1 more source
Chiral nanoprobes for targeting and long-term imaging of the Golgi apparatus
The targeting and long-term imaging of the Golgi apparatus have been realized via l-cysteine functionalized nanoprobes.
R. Li +9 more
semanticscholar +1 more source
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]
Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Falguières, Thomas +15 more
core +1 more source
Bridging the gap between glycosylation and vesicle traffic
Glycosylation is recognised as a vitally important posttranslational modification. The structure of glycans that decorate proteins and lipids is largely dictated by biosynthetic reactions occurring in the Golgi apparatus.
Daniel eUngar, Peter eFisher
doaj +1 more source
Associating bovine herpesvirus 1 envelope glycoprotein gD with activated phospho-PLC-γ1(S1248)
Phospholipase C gamma 1 (PLC-γ1) may locate at distinct subcellular locations, such as cytosol, plasma membrane, and nucleus for varied biological functions.
Chang Liu +8 more
doaj +1 more source
Golgi Dynamics: The Morphology of the Mammalian Golgi Apparatus in Health and Disease
In vertebrate cells the Golgi consists of individual stacks fused together into a compact ribbon structure. The function of the ribbon structure of the Golgi has only begun to be appreciated (De Matteis et al., 2008; Gosavi and Gleeson, 2017; Wei and ...
Christian Makhoul +2 more
semanticscholar +1 more source
"In vitro" reconstitution of "trans"-Golgi exit and the effect of GAG attachment on protein sorting [PDF]
The trans-Golgi network is one of the main sorting stations for proteins and lipids in the eukaryotic endomembrane system. Yet, the mechanisms for sorting and transport out of the trans-Golgi network remain poorly understood.
Kobialka, Szymon
core +1 more source

