Identification, by a monoclonal antibody, of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus [PDF]
, 1988 Purified Golgi membranes of the human intestinal adenocarcinoma cell line Caco-2 were used as an antigen to produce a monoclonal antibody, G1/93, which specifically labels a tubulovesicular compartment near the cis side of the Golgi apparatus, including ...
Bachi, T. +9 more
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The Golgi apparatus in neurorestoration
Journal of Neurorestoratology, 2019 The central role of the Golgi apparatus in critical cellular processes such as the transport, processing, and sorting of proteins and lipids has placed it at the forefront of cell science.
Jianyang Liu +5 more
doaj +1 more source
An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning. [PDF]
PLoS Biology, 2011 The elaboration of dendrites in neurons requires secretory trafficking through the Golgi apparatus, but the mechanisms that govern Golgi function in neuronal morphogenesis in the brain have remained largely unexplored.
Nadia Litterman +7 more
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Characterization of p28, a novel ERGIC/"cis"-Golgi protein, required for Golgi ribbon formation. pH measurements in the early secretory pathway "in vivo" [PDF]
, 2008 The secretory pathway of mammalian cells consists of several compartments. Transport between these organelles is accomplished via vesicular carriers or maturation. For non abundant proteins it is thought that transport receptors help the proteins to exit
Kögler, Eva Jutta
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The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network [PDF]
, 2008 The small-molecule inhibitor Exo2 {4-hydroxy-3-methoxy-(5,6,7,8-tetrahydrol[1]benzothieno[2,3-d]pyrimidin-4-yl)hydraz-one benzaldehyde} has been reported to disrupt the Golgi apparatus completely and to stimulate Golgi–ER (endoplasmic reticulum) fusion ...
Amessou, M +37 more
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Cytoplasmic dynein and its regulatory proteins in Golgi pathology in nervous system disorders
Frontiers in Neuroscience, 2015 The Golgi apparatus is a dynamic organelle involved in processing and sorting of lipids and proteins. In neurons, the Golgi apparatus is important for the development of axons and dendrites and maintenance of their highly polarized morphology.
Dick eJaarsma, Casper eHoogenraad
doaj +1 more source
Targeting of protein ERGIC-53 to the ER/ERGIC/cis-Golgi recycling pathway [PDF]
, 1995 ERGIC-53 is a lectin-type membrane protein that continuously recycles between the ER, ER-Golgi intermediate compartment (ERGIC) and the cis-Golgi. To identify the targeting signals that mediate this recycling, N-glycosylated and myc-tagged variants of ...
R Schindler +5 more
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Genes and Diseases, 2023 Dendrites are specialized neuronal compartments that sense, integrate and transfer information in the neural network. Their development is tightly controlled and abnormal dendrite morphogenesis is strongly linked to neurological disorders.
Meilan Chen +4 more
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Golgi Dynamics in Physiological and Pathological Conditions
, 2020 Articles in this collection illustrate our recent progress in understanding Golgi biology, and also outline a specific set of yet unanswered Golgi-related questions.
core +2 more sources
The Stack of the Golgi Apparatus.
Archives of Histology and Cytology, 2002 One hundred years have passed since the discovery of "the internal reticular apparatus" by Camillo GOLGI. Investigations into the structure and function of the "Golgi apparatus" have raised more and more challenging issues for cell biologists. After long debate, many new findings have accumulated in the last 10 years as a result of the availability of ...
TAMAKI, Hideaki, YAMASHINA, Shohei
openaire +3 more sources