Results 21 to 30 of about 1,085,148 (332)

C11ORF24 is a novel type I membrane protein that cycles between the Golgi apparatus and the plasma membrane in Rab6-positive vesicles. [PDF]

open access: yesPLoS ONE, 2013
The Golgi apparatus is an intracellular compartment necessary for post-translational modification, sorting and transport of proteins. It plays a key role in mitotic entry through the Golgi mitotic checkpoint. In order to identify new proteins involved in
Vincent Fraisier   +12 more
doaj   +1 more source

A distinct Golgi-targeting mechanism of dGM130 in Drosophila neurons

open access: yesFrontiers in Molecular Neuroscience, 2023
GM130 is a matrix protein that is conserved in metazoans and involved in the architecture of the Golgi apparatus. In neurons, Golgi apparatus and dendritic Golgi outposts (GOs) have different compartmental organizations, and GM130 localization is present
Guo Cheng   +5 more
doaj   +1 more source

Direct trafficking pathways from the Golgi apparatus to the plasma membrane

open access: yesSeminars in Cell and Developmental Biology, 2020
In eukaryotic cells, protein sorting is a highly regulated mechanism important for many physiological events. After synthesis in the endoplasmic reticulum and trafficking to the Golgi apparatus, proteins sort to many different cellular destinations ...
Daniel Stalder, David C. Gershlick
semanticscholar   +1 more source

The asymmetrical structure of Golgi apparatus membranes revealed by in situ atomic force microscope. [PDF]

open access: yesPLoS ONE, 2013
The Golgi apparatus has attracted intense attentions due to its fascinating morphology and vital role as the pivot of cellular secretory pathway since its discovery.
Haijiao Xu   +5 more
doaj   +1 more source

Nonredundant Roles of GRASP55 and GRASP65 in the Golgi Apparatus and Beyond.

open access: yesTIBS -Trends in Biochemical Sciences. Regular ed, 2020
It has been demonstrated that two Golgi stacking proteins, GRASP55 and GRASP65, self-interact to form trans-oligomers that tether adjacent Golgi membranes into stacks and ribbons in mammalian cells.
Xiaoyan Zhang, Yanzhuang Wang
semanticscholar   +1 more source

Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]

open access: yes, 2013
Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Crawford, Sue E.   +4 more
core   +2 more sources

The Golgi apparatus in neurorestoration

open access: yesJournal of Neurorestoratology, 2019
The central role of the Golgi apparatus in critical cellular processes such as the transport, processing, and sorting of proteins and lipids has placed it at the forefront of cell science.
Jianyang Liu   +5 more
doaj   +1 more source

An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning. [PDF]

open access: yesPLoS Biology, 2011
The elaboration of dendrites in neurons requires secretory trafficking through the Golgi apparatus, but the mechanisms that govern Golgi function in neuronal morphogenesis in the brain have remained largely unexplored.
Nadia Litterman   +7 more
doaj   +1 more source

Re-defining the Golgi complex in Plasmodium falciparum using the novel Golgi marker PfGRASP [PDF]

open access: yes, 2005
Plasmodium falciparum, the causative agent of malaria, relies on a sophisticated protein secretion system for host cell invasion and transformation.
Cowman, Alan F.   +6 more
core   +1 more source

An ancestral secretory apparatus in the protozoan parasite Giardia intestinalis [PDF]

open access: yes, 2003
The protozoan parasite Giardia intestinalis belongs to one of the earliest diverged eukaryotic lineages. This is also reflected in a simple intracellular organization, as Giardia lacks common subcellular compartments such as mitochondria, peroxisomes ...
Hehl, Adrian B.   +7 more
core   +1 more source

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