Results 251 to 260 of about 3,145,194 (361)

Intracellular concentration and membrane permeability ratio of sodium and potassium ion in cultured cardiomyocytes of the adult rat.

, 1988
Adrian Sculptoreanu
openalex   +2 more sources

Studying the structure of the intracellular moiety of the insulin receptor with a kinase-splitting membranal proteinase [PDF]

, 1990
Thomas Braun, Eva Bober, Gregor Buschhausen-Denker, Stave Kohtz, K.-H. Grzeschik, Hans Henning   +5 more
openalex   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Coiled Coils in Both Intracellular Vesicle and Viral Membrane Fusion [PDF]

, 1998
J.J. Skehel, Don C. Wiley
openalex   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Tauroursodeoxycholic acid binds to the G-protein site on light activated rhodopsin [PDF]

, 2018
Kisselev, O. G, Lobysheva, E., Marshall, G. R, Taylor, C. M   +3 more
core   +2 more sources

Harnessing advanced computational approaches to design novel antimicrobial peptides against intracellular bacterial infections. [PDF]

Bioact Mater
Fang Y, Fan D, Feng B, Zhu Y, Xie R, Tan X, Liu Q, Dong J, Zeng W.   +8 more
europepmc   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

The intracellular targeting and membrane topology of 3-hydroxy-3-methylglutaryl-CoA reductase.

, 1992
E.H. Olender, Robert D. Simon
openalex   +1 more source

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

Advanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai, Zhelun Li, Wendong Gao, Yuqing Mu, Jiaying Liu, Yufeng Zhang, Xiaohan Mei, Jingjing Quan, Lan Xiao, Yin Xiao   +9 more
wiley   +1 more source