Results 31 to 40 of about 520,227 (253)

Contacting domains segregate a lipid transporter from a solute transporter in the malarial host–parasite interface

Nature Communications, 2020
While membrane contact sites between intracellular organelles are abundant, little is known about the contacts between membranes that delimit extracellular junctions within cells, such as intracellular parasites.
Matthias Garten, Josh R. Beck, Robyn Roth, Tatyana Tenkova-Heuser, John Heuser, Eva S. Istvan, Christopher K. E. Bleck, Daniel E. Goldberg, Joshua Zimmerberg   +8 more
doaj   +1 more source

Mutual Mobile Membranes with Timers [PDF]

Electronic Proceedings in Theoretical Computer Science, 2009
A feature of current membrane systems is the fact that objects and membranes are persistent. However, this is not true in the real world. In fact, cells and intracellular proteins have a well-defined lifetime.
Gabriel Ciobanu, Bogdan Aman
doaj   +1 more source

Interorganellar Membrane Microdomains: Dynamic Platforms in the Control of Calcium Signaling and Apoptosis

Cells, 2013
The dynamic interplay among intracellular organelles occurs at specific membrane tethering sites, where two organellar membranes come in close apposition but do not fuse.
Alessandra d'Azzo, Ida Annunziata
doaj   +1 more source

Characterization of Plasmodium vivax Early Transcribed Membrane Protein 11.2 and Exported Protein 1. [PDF]

PLoS ONE, 2015
In Plasmodium, the membrane of intracellular parasites is initially formed during invasion as an invagination of the red blood cell surface, which forms a barrier between the parasite and infected red blood cells in asexual blood stage parasites.
Yang Cheng, Feng Lu, Seong-Kyun Lee, Deok-Hoon Kong, Kwon-Soo Ha, Bo Wang, Jetsumon Sattabongkot, Takafumi Tsuboi, Eun-Taek Han   +8 more
doaj   +1 more source

High‐Efficient and Dosage‐Controllable Intracellular Cargo Delivery through Electrochemical Metal–Organic Hybrid Nanogates

Small Science, 2021
Hollow nanostructures combined with electroporation are potentially valuable in interdisciplinary fields due to their ability to transport versatile cargos into adhesive cells.
Bowen Zhang, Dinuo Zheng, Shi Yiming, Kazuhiro Oyama, Masahiro Ito, Masaomi Ikari, Takanori Kigawa, Tsutomu Mikawa, Takeo Miyake   +8 more
doaj   +1 more source

Transient features in nanosecond pulsed electric fields differentially modulate mitochondria and viability. [PDF]

PLoS ONE, 2012
It is hypothesized that high frequency components of nanosecond pulsed electric fields (nsPEFs), determined by transient pulse features, are important for maximizing electric field interactions with intracellular structures.
Stephen J Beebe, Yeong-Jer Chen, Nova M Sain, Karl H Schoenbach, Shu Xiao   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Galectin-3 (MAC-2) controls phagocytosis and macropinocytosis through intracellular and extracellular mechanisms

Frontiers in Cellular Neuroscience, 2022
Galectin-3 (Gal-3; formally named MAC-2) is a β-galactoside-binding lectin. Various cell types produce Gal-3 under either normal conditions and/or pathological conditions. Gal-3 can be present in cells' nuclei and cytoplasm, secreted from producing cells,
Shlomo Rotshenker
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source