Results 21 to 30 of about 520,227 (253)

Dengue virus infection perturbs lipid homeostasis in infected mosquito cells. [PDF]

PLoS Pathogens, 2012
Dengue virus causes ∼50-100 million infections per year and thus is considered one of the most aggressive arthropod-borne human pathogen worldwide.
Rushika Perera, Catherine Riley, Giorgis Isaac, Amber S Hopf-Jannasch, Ronald J Moore, Karl W Weitz, Ljiljana Pasa-Tolic, Thomas O Metz, Jiri Adamec, Richard J Kuhn   +9 more
doaj   +1 more source

Spatiotemporal three-dimensional transport dynamics of endocytic cargos and their physical regulations in cells

iScience, 2022
Summary: Intracellular transport, regulated by complex cytoarchitectures and active driving forces, is crucial for biomolecule translocations and relates to many cellular functions.
Chao Jiang, Mingcheng Yang, Wei Li, Shuo-Xing Dou, Peng-Ye Wang, Hui Li   +5 more
doaj   +1 more source

Two-Pore Channels Regulate Expression of Various Receptors and Their Pathway-Related Proteins in Multiple Ways

Cells, 2021
Two-pore channels (TPCs) constitute a small family of ion channels within membranes of intracellular acidic compartments, such as endosomes and lysosomes.
Sonja Grossmann, Robert Theodor Mallmann, Norbert Klugbauer   +2 more
doaj   +1 more source

Intracellular Membrane Traffic at High Resolution [PDF]

, 2010
Membrane traffic between organelles is essential for a multitude of processes that maintain cell homeostasis. Many steps in these tightly regulated trafficking pathways take place in microdomains on the membranes of organelles, which require analysis at nanometer resolution. Electron microscopy (EM) can visualize these processes in detail and is mainly
van Weering, JRT, Brown, E, Sharp, TH, Mantell, J, Cullen, PJ, Verkade, P   +5 more
openaire   +3 more sources

Cell Penetrating Peptides as Molecular Carriers for Anti-Cancer Agents

Molecules, 2018
Cell membranes with their selective permeability play important functions in the tight control of molecular exchanges between the cytosol and the extracellular environment as the intracellular membranes do within the internal compartments.
Antonella Borrelli, Anna Lucia Tornesello, Maria Lina Tornesello, Franco M. Buonaguro   +3 more
doaj   +1 more source

Metal-tagging Transmission Electron Microscopy for Localisation of Tombusvirus Replication Compartments in Yeast

Bio-Protocol, 2018
Positive-stranded (+) RNA viruses are intracellular pathogens in humans, animals and plants. To build viral replicase complexes (VRCs) viruses manipulate lipid flows and reorganize subcellular membranes.
Isabel Fernandez de Castro, Cristina Risco   +1 more
doaj   +1 more source

A bacteriophage endolysin that eliminates intracellular streptococci

eLife, 2016
PlyC, a bacteriophage-encoded endolysin, lyses Streptococcus pyogenes (Spy) on contact. Here, we demonstrate that PlyC is a potent agent for controlling intracellular Spy that often underlies refractory infections.
Yang Shen, Marilia Barros, Tarek Vennemann, D Travis Gallagher, Yizhou Yin, Sara B Linden, Ryan D Heselpoth, Dennis J Spencer, David M Donovan, John Moult, Vincent A Fischetti, Frank Heinrich, Mathias Lösche, Daniel C Nelson   +13 more
doaj   +1 more source

Lipid Phosphate Phosphatases and Cancer

Biomolecules, 2020
Lipid phosphate phosphatases (LPPs) are a group of three enzymes (LPP1–3) that belong to a phospholipid phosphatase (PLPP) family. The LPPs dephosphorylate a wide spectrum of bioactive lipid phosphates, among which lysophosphatidate (LPA) and sphingosine
Xiaoyun Tang, David N. Brindley
doaj   +1 more source

Viruses and Lipids

Viruses, 2010
As obligatory intracellular pathogens, viruses exploit various cellular molecules and structures, such as cellular membranes, for their propagation.
Akira Ono
doaj   +1 more source

Evaluation of Reference Gene Stability for Investigations of Intracellular Signalling in Human Cancer and Non-Malignant Mesenchymal Stromal Cells

Frontiers in Bioscience-Scholar
Background: Real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR) is a powerful tool for analysing target gene expression in biological samples.
Vera Kosheverova, Alexander Schwarz, Rimma Kamentseva, Marianna Kharchenko, Elena Kornilova   +4 more
doaj   +1 more source