Results 41 to 50 of about 796,901 (292)
Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication [PDF]
All positive strand RNA viruses are known to replicate their genomes in close association with intracellular membranes. In case of the hepatitis C virus (HCV), a member of the family Flaviviridae, infected cells contain accumulations of vesicles forming ...
Antony, Claude +13 more
core +3 more sources
Two-pore channels (TPCs) constitute a small family of ion channels within membranes of intracellular acidic compartments, such as endosomes and lysosomes.
Sonja Grossmann +2 more
doaj +1 more source
SpoT Induces Intracellular Salmonella Virulence Programs in the Phagosome. [PDF]
Guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), together named (p)ppGpp, regulate diverse aspects of Salmonella pathogenesis, including synthesis of nutrients, resistance to inflammatory mediators, and expression of secretion ...
Fitzsimmons, Liam F +8 more
core +1 more source
Cell Penetrating Peptides as Molecular Carriers for Anti-Cancer Agents
Cell membranes with their selective permeability play important functions in the tight control of molecular exchanges between the cytosol and the extracellular environment as the intracellular membranes do within the internal compartments.
Antonella Borrelli +3 more
doaj +1 more source
Manipulation of lipid rafts in neuronal cells [PDF]
Lipid rafts are specialized plasma membrane micro-domains highly enriched in cholesterol, sphingolipids and glycosylphosphatidylinositol (GPI) anchored proteins.
Eckert, Gunter P.
core +1 more source
Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules [PDF]
Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii).
Ferrari, G. +3 more
core +1 more source
Positive-stranded (+) RNA viruses are intracellular pathogens in humans, animals and plants. To build viral replicase complexes (VRCs) viruses manipulate lipid flows and reorganize subcellular membranes.
Isabel Fernandez de Castro +1 more
doaj +1 more source
PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer [PDF]
Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic wasting disease (CWD).
Barillas-Mury, C. +6 more
core +2 more sources
A bacteriophage endolysin that eliminates intracellular streptococci
PlyC, a bacteriophage-encoded endolysin, lyses Streptococcus pyogenes (Spy) on contact. Here, we demonstrate that PlyC is a potent agent for controlling intracellular Spy that often underlies refractory infections.
Yang Shen +13 more
doaj +1 more source
Lipid Phosphate Phosphatases and Cancer
Lipid phosphate phosphatases (LPPs) are a group of three enzymes (LPP1–3) that belong to a phospholipid phosphatase (PLPP) family. The LPPs dephosphorylate a wide spectrum of bioactive lipid phosphates, among which lysophosphatidate (LPA) and sphingosine
Xiaoyun Tang, David N. Brindley
doaj +1 more source

