Results 111 to 120 of about 365,824 (219)

Protective Effect and Mechanism of Edible Grass (Rumex patientia L. × Rumex tianschanicus A.LOS) Jiaosu on Alcohol-Induced Injury in HepG2 Cells [PDF]

Shipin Kexue
The protective effect of edible grass jiaosu (EGJ) on alcohol-induced injury in HepG2 cells was evaluated in terms of cell viability, alcohol dehydrogenase (ADH) activity, lactate dehydrogenase (LDH) activity, malondialdehyde (MDA) content and superoxide
LI Xianxiu, HE Tao, MAO Yangchen, MAO Jianwei, LAI Xiaojin, SHAO Yihuai, SHA Ruyi
doaj   +1 more source

Pharmacokinetic Model of Tenofovir and Emtricitabine and Their Intracellular Metabolites in Patients in the ANRS 134-COPHAR 3 Trial Using Dose Records. [PDF]

Antimicrob Agents Chemother, 2023
Bertrand J, Barrail-Tran A, Fayette L, Savic R, Goujard C, Teicher E, Barau C, Pruvost A, Taburet AM, Mentré F, Verstuyft C.   +10 more
europepmc   +1 more source

In vivo metabolite compartmentalization probed using intracellular GdDTPA [PDF]

, 2007
Fast trans-membrane water exchange enables in- tracellular relaxation enhancement of water by contrast agents in the extracellular space. For me- tabolites not in fast exchange across membranes, intracellular metabolite relaxation enhancement will only occur if the contrast agent and metabolite are in the same compartment.
Peters, David Alberg, Rowland, Ian
openaire  

Impact of Trans-Resveratrol-Sulfates and -Glucuronides on Endothelial Nitric Oxide Synthase Activity, Nitric Oxide Release and Intracellular Reactive Oxygen Species

Molecules, 2014
Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a polyphenolic natural product mainly present in grape skin, berries and peanuts. In the vasculature resveratrol is thought to boost endothelial function by increasing endothelial nitric oxide synthase ...
Angela Ladurner, Daniel Schachner, Katharina Schueller, Marc Pignitter, Elke H. Heiss, Veronika Somoza, Verena M. Dirsch   +6 more
doaj   +1 more source

Acylation driven by intracellular metabolites in host cells inhibits Cas9 activity used for genome editing. [PDF]

PNAS Nexus, 2022
Zhao L, You D, Wang T, Zou ZP, Yin BC, Zhou Y, Ye BC.   +6 more
europepmc   +1 more source

The development of metabolomic sampling procedures for Pichia pastoris, and baseline metabolome data.

PLoS ONE, 2011
Metabolic profiling is increasingly being used to investigate a diverse range of biological questions. Due to the rapid turnover of intracellular metabolites it is important to have reliable, reproducible techniques for sampling and sample treatment ...
Gregory D Tredwell, Bryn Edwards-Jones, David J Leak, Jacob G Bundy   +3 more
doaj   +1 more source

Discovery of Novel Doxorubicin Metabolites in MCF7 Doxorubicin-Resistant Cells

Frontiers in Pharmacology, 2019
Doxorubicin (DOX) is metabolized to a variety of metabolites in vivo, which has been shown to be associated with cardiotoxicity. We speculate that metabolic processes are also present in tumor cells.
Xu Wang, Renjie Hui, Yun Chen, Wentao Wang, Yujiao Chen, Xiaohai Gong, Jian Jin   +6 more
doaj   +1 more source

An Integrated Analysis of Intracellular Metabolites and Virulence Gene Expression during Biofilm Development of a Clinical Isolate of Candida tropicalis on Distinct Surfaces. [PDF]

Int J Mol Sci, 2021
Salvatore MM, Maione A, Albarano L, de Alteriis E, Carraturo F, Andolfi A, Salvatore F, Galdiero E, Guida M.   +8 more
europepmc   +1 more source

Microbiota-Produced N-Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance. [PDF]

, 2019
The composition of the gastrointestinal microbiota and associated metabolites changes dramatically with diet and the development of obesity. Although many correlations have been described, specific mechanistic links between these changes and glucose ...
Chan, Luisa S, Chordia, Mahendra D, El Ouarrat, Dalila, Han, Andrew W, Jain, Mohit, Johnson, Andrew MF, Lee, Yun Sok, Mahmood, Nadir A, Ofrecio, Jachelle M, Olefsky, Jerrold M, Pan, Dongfeng, Riopel, Matthew, Ryan, Caitlin N, Watrous, Jeramie D, Wollam, Joshua, Xu, Yong-Jiang, Ying, Wei   +16 more
core   +1 more source

Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results [PDF]

, 2009
*Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Arun Agrawala, Madan Rehani, Rakesh Sharma   +2 more
core   +1 more source