Results 11 to 20 of about 365,824 (219)
Scalable computation of intracellular metabolite concentrations [PDF]
Computers & Chemical Engineering, 2021 Current mathematical frameworks for predicting the flux state and macromolecular composition of the cell do not rely on thermodynamic constraints to determine the spontaneous direction of reactions. These predictions may be biologically infeasible as a result.
Akbari, Amir, Palsson, Bernhard O.
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Emergence of Metabolite Provisioning as a By-Product of Evolved Biological Functions
mSystems, 2020 Microbes commonly use metabolites produced by other organisms to compete effectively with others in their environment. As a result, microbial communities are composed of networks of metabolically interdependent organisms.
Sebastian Gude +2 more
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mSystems, 2021 Global transcriptional regulators coordinate complex genetic interactions that bestow better adaptability for an organism against external and internal perturbations.
Mahesh S. Iyer +4 more
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A Salvaging Strategy Enables Stable Metabolite Provisioning among Free-Living Bacteria
mSystems, 2022 All organisms rely on complex metabolites such as amino acids, nucleotides, and cofactors for essential metabolic processes. Some microbes synthesize these fundamental ingredients of life de novo, while others rely on uptake to fulfill their metabolic ...
Sebastian Gude +2 more
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Intracellular Metabolite Transporters in Plants [PDF]
Molecular Plant, 2010 Due to the presence of plastids, eukaryotic photosynthetic cells represent the most highly compartmentalized eukaryotic cells. This high degree of compartmentation requires the transport of solutes across intracellular membrane systems by specific membrane transporters.
Linka, Nicole, Weber, Andreas P.M.
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Frontiers in Microbiology, 2021 Rosa roxburghii Tratt. is widely applied in food, cosmetics, and traditional medicine, and has been demonstrated to possess diverse bioactivities. Plant endophytic fungi are important microbial resources with great potential for application in many ...
Hong Zhang +9 more
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Intracellular compartmentation and transport of metabolites [PDF]
Journal of Supramolecular Structure, 1978 AbstractThe intracellular locations of enzymes and metabolites were determined for ornithine metabolism in Neurospora. Pulse label experiments were used to measure the rates of intracellular translocations and the sizes of compartmented pools of metabolites in the mitochondrial, cytosolic and vesicular compartments.
Davis, Rowland H +2 more
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Open Biology, 2022 Evolution facilitates emergence of fitter phenotypes by efficient allocation of cellular resources in conjunction with beneficial mutations. However, system-wide pleiotropic effects that redress the perturbations to the apex node of the transcriptional ...
Ankita Pal +4 more
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Near-Critical Phenomena in Intracellular Metabolite Pools [PDF]
Biophysical Journal, 2003 The supply and consumption of metabolites in living cells are catalyzed by enzymes. Here we consider two of the simplest schemes where one substrate is eliminated through Michaelis-Menten kinetics, and where two types of substrates are joined together by an enzyme. It is demonstrated how steady-state substrate concentrations can change ultrasensitively
Elf, Johan +3 more
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Frontiers in Microbiology, 2023 Many studies have focused on the influence of dietary supplements on gut microbiota composition, but limited research have reported their effects on specific bacterial species in the gut.
Ziyan Wang +31 more
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