BCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium berghei [PDF]
, 2014 While the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii are thought to primarily depend on glycolysis for ATP synthesis, recent studies have shown that they can fully catabolize glucose in a canonical TCA cycle.
Barrett, Michael P. +11 more
core +1 more source
Frontiers in Microbiology, 2020 Elucidating the metabolite profiles during the growth of Streptococcus thermophilus is beneficial for understanding its growth characteristics. The changes in the intracellular and extracellular concentrations of carbohydrates, nucleotides, amino sugars,
Yali Qiao +7 more
doaj +1 more source
Comparative metabolomics profiling of engineered Saccharomyces cerevisiae lead to a strategy that improving β-carotene production by acetate supplementation. [PDF]
PLoS ONE, 2017 A comparative metabolomic analysis was conducted on recombinant Saccharomyces cerevisiae strain producing β-carotene and the parent strain cultivated with glucose as carbon source using gas chromatography-mass spectrometry (GC-MS), high performance ...
Xiao Bu +3 more
doaj +1 more source
Quantifying biosynthetic network robustness across the human oral microbiome [PDF]
, 2018 Metabolic interactions, such as cross-feeding, play a prominent role in microbial communitystructure. For example, they may underlie the ubiquity of uncultivated microorganisms.
Bernstein, David +2 more
core +1 more source
Visualization of metabolic interaction networks in microbial communities using VisANT 5.0 [PDF]
, 2016 The complexity of metabolic networks in microbial communities poses an unresolved visualization and interpretation challenge. We address this challenge in the newly expanded version of a software tool for the analysis of biological networks, VisANT 5.0 ...
Chang, Yi-Chien +5 more
core +4 more sources
Metabolic network percolation quantifies biosynthetic capabilities across the human oral microbiome [PDF]
, 2019 The biosynthetic capabilities of microbes underlie their growth and interactions, playing a prominent role in microbial community structure. For large, diverse microbial communities, prediction of these capabilities is limited by uncertainty about ...
Bernstein, David B. +2 more
core +1 more source
Error Propagation Analysis for Quantitative Intracellular Metabolomics
Metabolites, 2012 Model-based analyses have become an integral part of modern metabolic engineering and systems biology in order to gain knowledge about complex and not directly observable cellular processes. For quantitative analyses, not only experimental data, but also
Jana Tillack +4 more
doaj +1 more source
Inositols in Insulin Signaling and Glucose Metabolism [PDF]
, 2018 In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Bevilacqua, Arturo, Bizzarri, Mariano
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Relationship between glycolysis and exopolysaccharide biosynhesis in Lactococcus lactis [PDF]
, 2001 The relationships between glucose metabolism and exopolysaccharide (EPS) production in a Lactococcus lactis strain containing the EPS gene cluster (Eps ) and in nonproducer strain MG5267 (Eps) were characterized.
Ramos, A. +3 more
core +1 more source
Sensors, 2019 Lab-on-a-chip sensing technologies have changed how cell biology research is conducted. This review summarises the progress in the lab-on-a-chip devices implemented for the detection of cellular metabolites.
Esma Dervisevic +3 more
doaj +1 more source