Results 231 to 240 of about 65,062 (302)

Host-directed therapeutic strategies against apicomplexan parasites: targeting purinergic P2 receptors. [PDF]

Purinergic Signal
Chaves MM, Carvalho-Barbosa N, Savio LEB, Coutinho-Silva R.   +3 more
europepmc   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

More than malaria: Exploring <i>Babesia</i>, <i>Leishmania</i> and <i>Trypanosoma</i> in sickle cell disease. [PDF]

Curr Res Parasitol Vector Borne Dis
Bhosale CR, Morcos ZL, Escudero A, Neupane R, Kahook Z, Miranda G, Deehan E, Gregg RK, Potter AK.   +8 more
europepmc   +1 more source

Bone Grafts: Everything You Need to Know

Journal of Periodontal Research, EarlyView.
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen, Javier Sanz, Giuseppe Perale, Augustine Mark Saiz, Mario Romandini, Maryam Rahmati   +5 more
wiley   +1 more source

Synergy between upregulated small GTPase immunity-associated proteins and lysosomal ATP6V1D in restricting intracellular <i>Toxoplasma</i> growth. [PDF]

Microbiol Spectr
Mia MM, Khan SM, Azam AR, Reilly J, Witola WH.   +4 more
europepmc   +1 more source

Pharmacokinetics of Diclazuril in the Plasma and Cerebrospinal Fluid of Healthy Adult Horses After a Single Oral Dose Administered as a Pelleted Topdressing

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Equine protozoal myeloencephalitis can cause acute infections with rapid onset of neurologic signs, necessitating immediate empiric therapy with antiprotozoal medication. The objective of the study was to identify when concentrations of diclazuril reached the MIC of Sarcocystis neurona in CSF (1 ng/mL) of healthy adult horses after a single ...
Elizabeth J. Treece, Kate L. Hepworth‐Warren, Mark G. Papich, Philip D. van Harreveld, Anthony T. Blikslager, Faith E. Church, Kaitlyn B. Harbor, Sara J. Erwin‐Craig   +7 more
wiley   +1 more source

Targeting Leishmania donovani Sphingosine Kinase 1 using PF-543 enhances immune response and limits parasite load. [PDF]

PLoS Negl Trop Dis
Madan E, Bansal R, Singhal J, Joshi N, Saini M, Shafi S, Gupta A, Singh S.   +7 more
europepmc   +1 more source

Histopathological investigation of wound healing activities of Lucilia sericata Larva and Achillea sintenisii extract combinations in diabetic rat wound model

Medical and Veterinary Entomology, EarlyView.
Lucilia sericata larvae secrete bioactive compounds that promote wound debridement and antimicrobial defence in chronic tissue injuries. Achillea sintenisii extract offers phytotherapeutic support, enhancing healing through anti‐inflammatory and regenerative properties. Diabetic Wistar rats were treated topically with Furacin®, larval secretions, plant
Nevra Polat, Salih Mollahaliloğlu, Murat Koç   +2 more
wiley   +1 more source

Harnessing <i>Toxoplasma gondii</i> microneme proteins for serodiagnosis and vaccine development: a review. [PDF]

Ann Med
Ji Y, Wang Z, Feng Y, Ahmad I, Alzahrani KJ, Alsharif KF, Alzahrani FM, Zhao X, Qadeer A, Liu W.   +9 more
europepmc   +1 more source

Turnip mosaic virus utilizes the lipid droplet biogenesis machinery to facilitate its propagation in plants

New Phytologist, EarlyView.
Potyvirus turnip mosaic virus induces neutral lipid accumulation and lipid droplet biogenesis in infected leaves for its own benefit. Summary Lipid droplets (LDs), which are dedicated to storing neutral lipids (NLs), are dynamic organelles involved in numerous other functions, including membrane remodeling during abiotic stress.
Léna Jambou, Nathalie Arvy, Marguerite Batsale, Luc Sofer, Sara Shakir, Marielle Cochet, Vincent Simon, Charlotte Quinteau, Thomas Scotti, Nathan M. Doner, Satinder K. Gidda, Robert T. Mullen, Sabine D'Andréa, Jean‐Luc Gallois, Denis Coulon, Claire Bréhélin, Sylvie German‐Retana   +16 more
wiley   +1 more source