Results 111 to 120 of about 67,933 (309)

Still frame from the hour of death: Acute intracerebral hemorrhage on post-mortem computed tomography in a decomposed corpse

, 2013
We report a case of an acute hypertensive, intracerebral hemorrhage on post-mortem computed tomography (PMCT) in a decomposed corpse. In clinical radiology, the appearance of blood on cross-sectional imaging is used to estimate the age of intracranial ...
Thali, Michael J., Thali, Michael J, Ross, Steffen, Ruder, Thomas, Ampanozi, Garyfalia; https://orcid.org/, Flach, Patricia M., Ruder, Thomas D, Zech, Wolf-Dieter, Hatch, Gary M, Ampanozi, Garyfalia, Flach, Patricia M, Hatch, Gary M.   +11 more
core   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

Statins and Intracerebral Hemorrhage

, 2011
Background— A recent large, randomized trial suggested that statins may increase the risk of intracerebral hemorrhage. Accordingly, we systematically reviewed the association of statins with intracerebral hemorrhage in randomized
Stephen MacMahon, Shinichiro Uchiyama, Daniel G. Hackam, Muhammad Mamdani, David L. Tirschwell, Yasuo Ikeda, Yea-Huei Kao Yang, Hisatomi Arima, Mark Woodward, Ching-Lan Cheng, David J. Werring, John Chalmers, Marko Mrkobrada, Maria I. Aguilar, Anand Viswanathan, Bruce M. Psaty, L. Kristin Newby, Mei-Shu Lai, Deepak L. Bhatt, Allan Donner, Cheryl D. Bushnell, James D. Douketis, Mingyuan Shao, Nicolas Danchin, Eric E. Smith, B. Marianne Verdel, Takenori Yamaguchi, Paola De Rango, Dan J. Capampangan, James Kennedy   +29 more
core   +1 more source

Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen, Tao‐Tao Shi, Dan‐Yang Hu, Xiao‐Na Su, Jian‐Xiang Jin, Mao‐Song Chen, Hao Wang, Wei Chen   +7 more
wiley   +1 more source

Nationwide Big Data Analysis of Statin Use and Intracerebral Hemorrhage Risk in Acute Ischemic Stroke Patients in Taiwan

Medicina
Background and Objectives: Although statins are recommended for secondary prevention of acute ischemic stroke, some population-based studies and clinical evidence suggest that they might be used with an increased risk of intracranial hemorrhage.
William Winardi, Sin-Hua Moi, Thomas Winardi, Yu-Wen Cheng, Po-Yuan Chen, Cheng-Kai Lin   +5 more
doaj   +1 more source

Neuroprotective Strategies for Intracerebral Hemorrhage

, 2010
Intracerebral hemorrhage is a devastating neurological illness with few treatment options. In the past 10 years, 6 clinical trials have been completed examining the potential role that putative neuroprotective agents might play in improving outcome ...
Christopher P. Kellner, E. Sander Connolly   +1 more
core   +1 more source

Impact of Proton Pump Inhibitor Use on Outcomes Following Carotid Artery Stenting for Asymptomatic Carotid Stenosis: A Population‐Based Cohort Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Carotid artery stenting (CAS) is an effective treatment for carotid stenosis. Proton‐pump inhibitors (PPIs) are commonly prescribed in the general population. However, the impact of PPI use on outcomes following CAS remains unknown. This study investigated the impact of PPI use on CAS using a retrospective, matched‐cohort analysis from the ...
Chia‐En Wong, Pang‐Shuo Perng, Pei‐Wen Chen, Yu Chang, Chih‐Hao Tien, Jung‐Shun Lee, Liang‐Chao Wang, Chih‐Yuan Huang   +7 more
wiley   +1 more source

Ginsenoside Rg1 Ameliorates LPS‐Induced Sepsis‐Associated Lung Injury in Mice via VEGFC/D‐VEGFR3 Signaling‐Mediated Lymphangiogenesis and Lymphatic Remodeling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang, Lan Hu, Chun‐Pan Zhang, Wen‐Jie Qi, Yu‐Guo Song   +4 more
wiley   +1 more source

NLRP3 inflammasome and gut microbiota–brain axis: A new perspective on white matter injury after intracerebral hemorrhage

Neural Regeneration Research
Intracerebral hemorrhage is the most dangerous subtype of stroke, characterized by high mortality and morbidity rates, and frequently leads to significant secondary white matter injury.
Xiaoxi Cai, Xinhong Cai, Quanhua Xie, Xueqi Xiao, Tong Li, Tian Zhou, Haitao Sun   +6 more
doaj   +1 more source

Rivaroxaban plasma levels in acute ischemic stroke and intracerebral hemorrhage

, 2018
Information about Rivaroxaban plasma levels (RivLev) may guide treatment decisions in patients with acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH) taking ...
Thilemann, Sebastian, Kägi, Georg, Sandor, Peter S, Engelter, Stefan T, Cappellari, Manuel, Emmanuel De Maistre, De Marchis, Gian Marco, Manuel Cappellari, Susanne Wegener, Berge, Eivind, Sebastian Thilemann, De Maistre, Emmanuel, Nils Peters, Béjot, Yannick, Schädelin, Sabine, Stefan T. Engelter, Eivind Berge, Gian Marco De Marchis, Zini, Andrea, Monika Kapauer, Zedde, Marialuisa, David Werring, Alexandros A. Polymeris, null null, Guillaume Turc, Andrea Zini, Andreas Luft, Marcel Arnold, Kapauer, Monika, Patrik Michel, Seiffge, David J, Traenka, Christopher, Arnold, Marcel, Turc, Guillaume, Marialuisa Zedde, Fischer, Urs, Dimtrios A. Tsakiris, Sabine Schädelin, Cordonnier, Charlotte, Werring, David, Urs Fischer, Jochen Vehoff, Luft, Andreas, David J. Seiffge, Michel, Patrik, Ilaria Maestrini, Charlotte Cordonnier, Sirimarco, Gaia, Tsakiris, Dimitrios A, Bonati, Leo H, Leo H. Bonati, Vehoff, Jochen, Maestrini, Ilaria, Georg Kägi, Peters, Nils, Yannick Béjot, Gaia Sirimarco, Philippe A. Lyrer, Tsakiris, Dimtrios A, Lyrer, Philippe A, Polymeris, Alexandros A, Gilles Rodier, Rodier, Gilles, Christopher Traenka, Wegener, Susanne, Peter S. Sandor   +65 more
core   +1 more source