Results 121 to 130 of about 500,548 (294)

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

A Randomized, Sham‐Controlled Trial of Repetitive Transcranial Magnetic Stimulation Targeting M1 and S2 in Central Poststroke Pain: A Pilot Trial

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Central poststroke pain (CPSP), a neuropathic pain condition, is difficult to treat. Repetitive transcranial magnetic stimulation (rTMS) targeted to the primary motor cortex (M1) can alleviate the condition, but not all patients respond. We aimed to assess a promising alternative rTMS target, the secondary somatosensory cortex (S2),
Juhani Ojala, Jukka Vanhanen, Hanna Harno, Pantelis Lioumis, Selja Vaalto, Mari A. Kaunisto, Jukka Putaala, Marko Kangasniemi, Erika Kirveskari, Jyrki P. Mäkelä, Eija Kalso   +10 more
wiley   +1 more source

A GLCM Embedded CNN Strategy for Computer-aided Diagnosis in Intracerebral Hemorrhage [PDF]

arXiv, 2019
Computer-aided diagnosis (CADx) systems have been shown to assist radiologists by providing classifications of all kinds of medical images like Computed tomography (CT) and Magnetic resonance (MR). Currently, convolutional neural networks play an important role in CADx.
arxiv  

Nontraumatic Pediatric Intracerebral Hemorrhage.

Stroke, 2019
Pediatric intracerebral hemorrhage (pICH), which is a brain parenchymal bleed with or without intraventricular extension occurring between 29 days and 18 years of age, represents a large proportion of strokes during childhood.
G. Boulouis, T. Blauwblomme, J. Hak, S. Benichi, A. Kirton, P. Meyer, M. Chevignard, E. Tournier-Lasserve, M. Mackay, S. Chabrier, C. Cordonnier, M. Kossorotoff, O. Naggara   +12 more
semanticscholar   +1 more source

Intraparenchymal hemorrhage and cerebral venous thrombosis in an adult with congenital porencephalic cyst presenting for generalized tonic-clonic seizures

Radiology Case Reports, 2020
Prothrombotic conditions are known risk factors for porencephalic cyst formation and cerebral vein thrombosis. Intracerebral hemorrhage is a potential complication of a cerebral vein thrombosis.
Georges El Hasbani, MD, Alaa Balaghi, Richard Assaker, MD, Alberto Rojas, MD, Marcelo Troya, MD, Ahmad Kofahi, MD, Jean Pierre Assaker, MD, Chadi Diab, MD, Husayn Al Husayni, MD   +8 more
doaj  

Harmonic Mean Point Processes: Proportional Rate Error Minimization for Obtundation Prediction [PDF]

arXiv, 2019
In healthcare, the highest risk individuals for morbidity and mortality are rarely those with the greatest modifiable risk. By contrast, many machine learning formulations implicitly attend to the highest risk individuals. We focus on this problem in point processes, a popular modeling technique for the analysis of the temporal event sequences in ...
arxiv  

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

Advanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li, Nicolas De Jay, Shan‐Shan Zhang, Xin Fang, Supriya Sharma, Katrina A. Catalano, Venkatesh Sridharan, Zhaoqing Wang, Lei Zhao, Joseph D. Szustakowski, Ching‐Pin Chang, Joseph C. Maranville, Emily R. Holzinger, Erika M. Kvikstad   +13 more
wiley   +1 more source

Negative regulation of glial Tim‐3 inhibits the secretion of inflammatory factors and modulates microglia to antiinflammatory phenotype after experimental intracerebral hemorrhage in rats

CNS Neuroscience & Therapeutics, 2019
To investigate the critical role of Tim‐3 in the polarization of microglia in intracerebral hemorrhage (ICH)‐induced secondary brain injury (SBI).
Zhouqing Chen, Hao Yu, Haiying Li, Haitao Shen, Xiang Li, Juyi Zhang, Zhu-Wei Zhang, Zhong Wang, Gang Chen   +8 more
semanticscholar   +1 more source

Peripheral blood immune landscape and NXPE3 as a novel biomarker for hypertensive intracerebral hemorrhage risk prediction and targeted therapy

iMeta, EarlyView.
We employed bulk RNA‐seq and scRNA‐seq techniques to analyze the immune dysregulation in patients with intracerebral hemorrhage (ICH). The study revealed that excessive inflammatory responses, neutrophil activation, and T‐cell dysfunction are the main characteristics of ICH.
Meng Zhang, Jingyuan Ning, Jing Liu, Yingying Sun, Ning Xiao, Haochen Xu, Jingzhou Chen   +6 more
wiley   +1 more source

The Frequency of Recurrence in Primary Hypertensive Intracerebral Hemorrhage

Journal of Research in Medical Sciences, 2006
Background: Primary intracerebral Hemorrhage (PICH) is a devasting illness with high early mortality which causes 10 -12 percent of stroke cases. Survivors of PICH are at risk for recurrence of hemorrhage.
SA Mousavi, SM Nourian, M Zare
doaj