Results 21 to 30 of about 98,762 (271)

Gavestinel does not improve outcome after acute intracerebral hemorrhage: an analysis from the GAIN International and GAIN Americas studies [PDF]

open access: yes, 2005
<p><b>Background and Purpose:</b> Glycine Antagonist in Neuroprotection (GAIN) International and GAIN Americas trials were prospectively designed, randomized, placebo-controlled trials of gavestinel, a glycine-site antagonist and ...
Brown, D.L.   +9 more
core   +1 more source

Intracerebral Hemorrhage and Ischemic Stroke of Different Etiologies Have Distinct Alternatively Spliced mRNA Profiles in the Blood: a Pilot RNA-seq Study. [PDF]

open access: yes, 2015
Whole transcriptome studies have used 3'-biased expression microarrays to study genes regulated in the blood of stroke patients. However, alternatively spliced messenger RNA isoforms have not been investigated for ischemic stroke or intracerebral ...
Ander, Bradley P   +8 more
core   +2 more sources

Prognostic Tools for Early Mortality in Hemorrhagic Stroke: Systematic Review and Meta-Analysis [PDF]

open access: yes, 2015
Background and Purpose: Several risk scores have been developed to predict mortality in intracerebral hemorrhage (ICH). We aimed to systematically determine the performance of published prognostic tools.
Agarwal   +28 more
core   +1 more source

Construction of risk prediction and early warning model for long⁃term hemodialysis patients with secondary intracerebral hemorrhage

open access: yesHuli yanjiu, 2022
ObjectiveTo explore the risk factors of secondary intracerebral hemorrhage in long⁃term hemodialysis patients,and establish the Nomograph model.MethodsA total of 204 end⁃stage uremia patients who underwent long⁃term hemodialysis were selected as the ...
LI Danni   +3 more
doaj  

Blood-Brain Barrier Dysfunction in Small Vessel Disease Related Intracerebral Hemorrhage

open access: yesFrontiers in Neurology, 2018
Background and Purpose: Hypertensive vasculopathy and cerebral amyloid angiopathy are the two most common forms of cerebral small vessel disease.
Whitney M. Freeze   +8 more
doaj   +1 more source

Application of stem cells and exosomes in the treatment of intracerebral hemorrhage: an update

open access: yesStem Cell Research & Therapy, 2022
Non-traumatic intracerebral hemorrhage is a highly destructive intracranial disease with high mortality and morbidity rates. The main risk factors for cerebral hemorrhage include hypertension, amyloidosis, vasculitis, drug abuse, coagulation dysfunction,
Jian-feng Zhou   +10 more
doaj   +1 more source

P2X7 receptor activation aggravates NADPH oxidase 2-induced oxidative stress after intracerebral hemorrhage

open access: yesNeural Regeneration Research, 2021
Oxidative stress is a crucial pathological process that contributes to secondary injury following intracerebral hemorrhage. P2X7 receptor (P2X7R), which is activated by the abnormal accumulation of extracellular ATP, plays an important role in the ...
Hong Deng   +11 more
doaj   +1 more source

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial [PDF]

open access: yes, 2019
Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy.
Abano, Nenette   +966 more
core   +5 more sources

Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial [PDF]

open access: yes, 2019
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage.
Al-Shahi Salman, Rustam   +16 more
core   +1 more source

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