Symptomatic intracerebral hemorrhage is a serious potential complication of recombinant tissue-type plasminogen activator thrombolysis in acute ischemic stroke.
Tingting Yuan +3 more
doaj +1 more source
Relationship Between Intracerebral Hemorrhage and Diabetes Mellitus: A Case-Control Study [PDF]
Introduction: The role of diabetes mellitus in the pathogenesis of intracerebral hemorrhage (ICH) is controversial. Underlying comorbidities such as diabetes mellitus may increase the risk of intracerebral hemorrhage.
Omid Hesami +5 more
doaj +1 more source
Summary: Intracerebral hemorrhage usually manifests as strong neuroinflammation and neurological deficits. There is an urgent need to explore effective methods for the treatment of intracerebral hemorrhage.
Jiaxin Liu +9 more
doaj +1 more source
Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Emiri Mandeville +44 more
core +2 more sources
Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT trial [PDF]
<p><b>Background and Purpose:</b> NXY-059 is a free radical-trapping neuroprotectant developed for use in acute ischemic stroke. To facilitate prompt administration of treatment, potentially before neuroimaging, we investigated the ...
Lyden, P.D. +12 more
core +1 more source
Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Demchuk, A. +8 more
core +1 more source
Is hypertension a more frequent risk factor for deep than for lobar supratentorial intracerebral haemorrhage? [PDF]
OBJECTIVE: To determine whether evidence from observational studies supports the widely held belief that hypertension is more commonly a risk factor for deep than for lobar supratentorial intracerebral haemorrhage.METHODS: Studies comparing the frequency
Jackson, C. A. +3 more
core +1 more source
Blood levels of Glial Fibrillary Acidic Protein (GFAP) in patients with neurological diseases [PDF]
Background and Purpose: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke.
Niessner, Marion +11 more
core +2 more sources
Iodinated contrast media and cerebral hemorrhage after intravenous thrombolysis [PDF]
<p>Background and Purpose: Iodinated contrast is increasingly used in CT perfusion or angiographic examinations in acute stroke. Increased risk of intracranial hemorrhage (ICH) complicating microcatheter contrast injections has recently been ...
McVerry, F. +11 more
core +1 more source
ObjectiveTo explore the risk factors of secondary intracerebral hemorrhage in long⁃term hemodialysis patients,and establish the Nomograph model.MethodsA total of 204 end⁃stage uremia patients who underwent long⁃term hemodialysis were selected as the ...
LI Danni +3 more
doaj

