Results 41 to 50 of about 186,103 (211)

Application of stem cells and exosomes in the treatment of intracerebral hemorrhage: an update

Stem Cell Research & Therapy, 2022
Non-traumatic intracerebral hemorrhage is a highly destructive intracranial disease with high mortality and morbidity rates. The main risk factors for cerebral hemorrhage include hypertension, amyloidosis, vasculitis, drug abuse, coagulation dysfunction,
Jian-feng Zhou, Yu Xiong, Xiaodong Kang, Zhigang Pan, Qiangbin Zhu, Roland Goldbrunner, Lampis Stavrinou, Shu Lin, Weipeng Hu, Feng Zheng, Pantelis Stavrinou   +10 more
doaj   +1 more source

P2X7 receptor activation aggravates NADPH oxidase 2-induced oxidative stress after intracerebral hemorrhage

Neural Regeneration Research, 2021
Oxidative stress is a crucial pathological process that contributes to secondary injury following intracerebral hemorrhage. P2X7 receptor (P2X7R), which is activated by the abnormal accumulation of extracellular ATP, plays an important role in the ...
Hong Deng, Ye Zhang, Gai-Gai Li, Hai-Han Yu, Shuang Bai, Guang-Yu Guo, Wen-Liang Guo, Yang Ma, Jia-Hui Wang, Na Liu, Chao Pan, Zhou-Ping Tang   +11 more
doaj   +1 more source

Blood-Brain Barrier Dysfunction in Small Vessel Disease Related Intracerebral Hemorrhage

Frontiers in Neurology, 2018
Background and Purpose: Hypertensive vasculopathy and cerebral amyloid angiopathy are the two most common forms of cerebral small vessel disease.
Whitney M. Freeze, Whitney M. Freeze, Heidi I. L. Jacobs, Heidi I. L. Jacobs, Floris H. B. M. Schreuder, Robert J. van Oostenbrugge, Walter H. Backes, Frans R. Verhey, Catharina J. M. Klijn   +8 more
doaj   +1 more source

Thrombolysis in a stroke patient on dabigatran anticoagulation: case report and synopsis of published cases [PDF]

, 2013
We present the case of an aphasic 77-year-old stroke patient with left distal M1 occlusion who received rt-PA for thrombolysis while on oral anticoagulant treatment with dabigatran (150 mg b.i.d.).
Baas, Horst, Mario Abruscato, Susanne Hövelmann, Pfeilschifter, Waltraud, Abruscato, Mario Giovanni Rosario, Hövelmann, Susanne, Horst Baas, Waltraud Pfeilschifter   +7 more
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Establishment of risk prediction model of occurrence of pulmonary embolism in patients with intracerebral hemorrhage

Huli yanjiu, 2023
ObjectiveTo explore risk factors of occurrence of pulmonary embolism in patients with intracerebral hemorrhage，and establish risk prediction model.Methods213 patients with intracerebral hemorrhage accepted by our hospital from July 2017 to October 2019 ...
DENG Tianfang, SHAO Shirong, CHEN Min, WANG Yan, YANG Guanglin   +4 more
doaj  

Associations of Clinical Characteristics and Etiology With Death in Hospitalized Chinese Children After Spontaneous Intracerebral Hemorrhage: A Single-Center, Retrospective Cohort Study

Frontiers in Pediatrics, 2021
Objective: We retrospectively analyzed clinical characteristics, etiology, and mortality risk factors in pediatric cases of non-traumatic spontaneous intracerebral hemorrhage.Methods: This study involved children between 29 days and 18 years old with ...
Xiaoyan Huang, Zicheng Cheng, Ye Xu, Lingfan Xia, Zhenxiang Zhan, Tong Xu, Yungang Cao, Zhao Han   +7 more
doaj   +1 more source

Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset [PDF]

, 2010
<p><b>Background and Purpose:</b> Antiplatelets (APs) may increase the risk of symptomatic intracerebral hemorrhage (ICH) following intravenous thrombolysis after ischemic stroke.</p> <p><b>Methods:</b> We ...
Wahlgren, N., Luijckx, G-J, Sykora, M., Wahlgren, N,, Diedler, J., Diedler, Jennifer, Overgaard, Karsten, Overgaard, K., Diedler, J, Ringleb, Peter, Uyttenboogaart, M., Ford, G.A., Soinne, Lauri, Overgaard, K, Lees, K.R., Lees, KR, Sykora, M, Uyttenboogaart, M, Uyttenboogaart, Maarten, Ringleb, P., Ahmed, Niaz, Luijckx, G.J., Luijckx, Gert-Jan, Ahmed, N,, Ahmed, N., Lees, Kennedy R., Wahlgren, Nils, Ford, GA, Soinne, L, Soinne, L., Sykora, Marek, Ford, Gary A., Uyttenboogaart, Maarten; id_orcid   +32 more
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The Effect of Hemorrhage Volume on Mortality in Spontaneous Intracerebral Hemorrhages

Van Tıp Dergisi, 2021
INTRODUCTION: Spontaneous intracerebral hemorrhage is associated with severe morbidity and mortality. In this study, it was aimed to investigate the effect of hemorrhage volume and other known prognostic factors on mortality in spontaneous intracerebral ...
İsmail Erkan Aydın, Çağdaş Yıldırım, Şeyda Tuba Savrun, Atakan Savrun, Alp Şener   +4 more
doaj   +1 more source

Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) [PDF]

, 2008
<p><b>Background and Purpose:</b> The Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) unadjusted results demonstrated that intravenous alteplase is well tolerated and that the effects were comparable with ...
Wahlgren, N., Dávalos A, Hennerici MG, Kaste, M., N. Eriksson, Toni, Danilo, Bluhmki, Erich, N. Wahlgren, Hacke, Werner, Köhrmann, Martin, M. Kaste, Eriksson, Niclas, Aichner F, Ahmed N, Hacke W, Eriksson, N., Koehrmann, M., Bluhmki E, Grond M, F. Aichner, V. Larrue, G. A. Ford, D. Toni, Kaste M, Larrue, Vincent, Erila, T., Larrue, V., Eriksson, Niclas,, Aichner, F., M. G. Hennerici, Wahlgren, Nils, Davalos, A., Ford, Gary A, Grond, M., Toni, D., K. R. Lees, null null, Hennerici, Michael G, T. Erila, Roine, Risto O, Hacke, W., Koehrmann, Martin, Davalos, Antoni, Eriksson N, W. Hacke, Larrue V, Erilä, Terttu, A. Davalos, Aichner, Franz, Bluhmki, E., Wahlgren N, Roine RO, Machnig, T., M. Grond, Vanhooren, Geert, Ford, G.A., Roine, R.O., Hennerici, Michael G., Lees, K.R., Roine, Risto O., E. Bluhmki, Hennerici, M.G., Lees KR, Grond, Martin, Kaste, Markku, Köhrmann M, Peeters, André, Ahmed, Niaz, Machnig, Thomas, Machnig T, Vanhooren G., Erilä T, M. Kohrmann, Ahmed, N., R. O. Roine, Lees, Kennedy R., Ford GA, G. Vanhooren, Vanhooren, G., Lees, Kennedy R, Ford, Gary A., T. Machnig, N. Ahmed, Grond, M, Wahlgren, N,, Aichner, F, Erila, T, Hacke, W, Davalos, A, Eriksson, N, Ford, GA, Ahmed, N,, Bluhmki, E   +92 more
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Progression of Traumatic Intracerebral Hemorrhage: A Prospective Observational Study

, 2008
Preliminary evidence has shown that intracerebral hemorrhages, either spontaneous (sICH) or traumatic (tICH) often expand over time. An association between hemorrhage expansion and clinical outcomes has been described for sICH.
Servadei, Franco, Skolnick, Brett E., Narayan, Raj K, Tillinger, Michael N, Tillinger, Michael N., and The Traumatic Intracerebral Hemorrhage Study Group, Maas, Andrew I.R, McCarthy, Mary C., Narayan, Raj K., Maas, Andrew I. R., Marshall, Lawrence F., Marshall, Lawrence F, Skolnick, Brett E, Maas, Andrew I.R.   +13 more
core   +1 more source