Results 61 to 70 of about 2,108 (162)
A prolonged experimental febrile seizure results in motor map reorganization in adulthood
Introduction: Clinical studies have suggested that children experiencing a febrile seizure (FS) before the age of 1 year have persistent deficits, but it is unknown whether these seizures lead to permanent cortical reorganization and alterations in ...
Aylin Y. Reid +2 more
doaj +1 more source
Post-ischemic reorganization of sensory responses in cerebral cortex
IntroductionSensorimotor integration is critical for generating skilled, volitional movements. While stroke tends to impact motor function, there are also often associated sensory deficits that contribute to overall behavioral deficits.
P. Hayley +6 more
doaj +1 more source
Changes in Spinal Neural Circuit Plasticity in a Rat Sciatic Nerve Transection Model
Following sciatic nerve transection (SNT), corticospinal tract (CST) labeling in the lumbar gray matter remained unchanged, whereas motor neurons showed soma atrophy with reduced perisomatic vesicular glutamate transporter 1 (vGlut1) and vesicular acetylcholine transporter (vAchT) inputs.
Katsuyuki Konishi +13 more
wiley +1 more source
Multi‐Channel Neural Interface for Neural Recording and Neuromodulation
This review highlights recent advances in multi‐channel neural interface technologies, covering both high‐resolution electrophysiological recording systems and multifunctional platforms with integrated capabilities. It also discusses innovations in structure and materials for reduced invasiveness, state‐of‐the‐art data analysis, including machine ...
Eunmin Kim +9 more
wiley +1 more source
Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex
Delivering light deep into the brain over a large volume while causing minimal tissue damage is a major challenge for non‐human primate optogenetics. This study evaluates Utah Optrode Array designs in vivo, revealing how changes in shank geometry, surface texture, and insertion parameters minimize acute damage—offering a path toward high‐precision ...
Adrián Villamarin‐Ortiz +8 more
wiley +1 more source
The somatotopic organization of the supplementary motor area: intracortical microstimulation mapping [PDF]
The somatotopic organization of the supplementary motor area (SMA) is commonly held to consist of a rostrocaudal sequence of orofacial, forelimb, and hindlimb representations. Recently, however, this somatotopy has been questioned. Studies of regional cerebral blood flow in humans and the movements evoked by intracortical electrical stimulation in ...
A R, Mitz, S P, Wise
openaire +2 more sources
Flexible thin‐film neural microelectrodes combining nanoporous reduced graphene oxide and a PI/Al2O3 hybrid encapsulation maintained stable electrochemical performance after soaking in PBS at 57 °C for over 377 days while they sustained the injection of 1 billion biphasic current pulses at high charge density (1 mC cm−2).
Georgios Alexandros Katirtsidis +5 more
wiley +1 more source
The functional consequences of chronic, physiologically effective intracortical microstimulation
Many studies have demonstrated the ability of chronically implanted multielectrode arrays (MEAs) to extract information from the motor cortex of both humans and nonhuman primates. Similarly, many studies have shown the ability of intracortical microstimulation to impart information to the brain via a single or a few electrodes acutely implanted in ...
Rebecca A, Parker +4 more
openaire +3 more sources
Toward Natural Limb Function: A New Era in Prosthetic Innovation
The past decade has witnessed groundbreaking clinical implementation of neuroprosthetic limbs driven by signals from peripheral targets (eg, nerves and muscle) and the brain to restore limb function for individuals with limb loss or impairment. In this review, we highlight recent key clinical trials in peripheral neuroprosthetic interfaces directly ...
Yucheng Tian +4 more
wiley +1 more source
Background A growing need exists for neuroscience platforms that can perform simultaneous chronic recording and stimulation of neural tissue in animal models in a telemetry-controlled fashion with signal processing for analysis of the chronic recording ...
John T. Ramshur +3 more
doaj +1 more source

