A prolonged experimental febrile seizure results in motor map reorganization in adulthood
Introduction: Clinical studies have suggested that children experiencing a febrile seizure (FS) before the age of 1 year have persistent deficits, but it is unknown whether these seizures lead to permanent cortical reorganization and alterations in ...
Aylin Y. Reid +2 more
doaj +1 more source
Post-ischemic reorganization of sensory responses in cerebral cortex
IntroductionSensorimotor integration is critical for generating skilled, volitional movements. While stroke tends to impact motor function, there are also often associated sensory deficits that contribute to overall behavioral deficits.
P. Hayley +6 more
doaj +1 more source
The somatotopic organization of the supplementary motor area: intracortical microstimulation mapping [PDF]
The somatotopic organization of the supplementary motor area (SMA) is commonly held to consist of a rostrocaudal sequence of orofacial, forelimb, and hindlimb representations. Recently, however, this somatotopy has been questioned. Studies of regional cerebral blood flow in humans and the movements evoked by intracortical electrical stimulation in ...
A R, Mitz, S P, Wise
openaire +2 more sources
Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex
Delivering light deep into the brain over a large volume while causing minimal tissue damage is a major challenge for non‐human primate optogenetics. This study evaluates Utah Optrode Array designs in vivo, revealing how changes in shank geometry, surface texture, and insertion parameters minimize acute damage—offering a path toward high‐precision ...
Adrián Villamarin‐Ortiz +8 more
wiley +1 more source
Optical imaging of cortical networks via intracortical microstimulation.
Understanding cortical organization is key to understanding brain function. Distinct neural networks underlie the functional organization of the cerebral cortex; however, little is known about how different nodes in the cortical network interact during perceptual processing and motor behavior. To study cortical network function we examined whether the
Brock AA, Friedman RM, Fan RH, Roe AW.
europepmc +4 more sources
Intact Bilateral Resting-State Networks in the Absence of the Corpus Callosum [PDF]
Temporal correlations between different brain regions in the resting-state BOLD signal are thought to reflect intrinsic functional brain connectivity (Biswal et al., 1995; Greicius et al., 2003; Fox et al., 2007).
Adolphs, Ralph +3 more
core +1 more source
Flexible thin‐film neural microelectrodes combining nanoporous reduced graphene oxide and a PI/Al2O3 hybrid encapsulation maintained stable electrochemical performance after soaking in PBS at 57 °C for over 377 days while they sustained the injection of 1 billion biphasic current pulses at high charge density (1 mC cm−2).
Georgios Alexandros Katirtsidis +5 more
wiley +1 more source
A Robust Encoding Scheme for Delivering Artificial Sensory Information via Direct Brain Stimulation [PDF]
Innovations for creating somatosensation via direct electrical stimulation of the brain will be required for the next generation of bi-directional cortical neuroprostheses.
Bjånes, David A., Moritz, Chet T.
core +1 more source
A low-cost programmable pulse generator for physiology and behavior [PDF]
Precisely timed experimental manipulations of the brain and its sensory environment are often employed to reveal principles of brain function. While complex and reliable pulse trains for temporal stimulus control can be generated with commercial ...
Kepecs, A., Sanders, J. I.
core +2 more sources
Toward Natural Limb Function: A New Era in Prosthetic Innovation
The past decade has witnessed groundbreaking clinical implementation of neuroprosthetic limbs driven by signals from peripheral targets (eg, nerves and muscle) and the brain to restore limb function for individuals with limb loss or impairment. In this review, we highlight recent key clinical trials in peripheral neuroprosthetic interfaces directly ...
Yucheng Tian +4 more
wiley +1 more source

