Results 71 to 80 of about 1,691 (139)

Targeted Sensory System Neuromodulation Improves Sensorimotor and Cognitive Deficits After Brain Injury: Bridging Mechanisms to Practice

Neural Plasticity, Volume 2025, Issue 1, 2025.
Brain injury, including stroke and traumatic brain injury (TBI), is a leading cause of death and disability worldwide, and limited spontaneous neuroplasticity often results in persistent neurological impairments. Neuromodulation has the potential to enhance brain reorganization, but when targeting motor pathways, it might yield unsatisfactory ...
Qin Zhang, Zhen Pang, Rongrong Lu, Hua He, Ulf Ziemann, Zhengrun Gao, Sergio Bagnato   +6 more
wiley   +1 more source

Restoring tactile and proprioceptive sensation through a brain interface

Neurobiology of Disease, 2015
Somatosensation plays a critical role in the dexterous manipulation of objects, in emotional communication, and in the embodiment of our limbs. For upper-limb neuroprostheses to be adopted by prospective users, prosthetic limbs will thus need to provide ...
Gregg A. Tabot, Sung Shin Kim, Jeremy E. Winberry, Sliman J. Bensmaia   +3 more
doaj   +1 more source

Intracortical microstimulation in humans: a decade of safety and efficacy

Abstract Background Intracortical microstimulation (ICMS) of somatosensory cortex can restore a sense of touch to people with spinal cord injury (SCI). In this early-feasibility clinical trial, we evaluate the safety, efficacy, and longevity of ICMS as there is a paucity of such long-term studies in ...
Charles M. Greenspon, Taylor G. Hobbs, Ceci Verbaarschot, Ali H. Alamri, Natalya D. Shelchkova, Robin Lienkämper, Joel Ye, Tyler W. Simpson, Jeffrey M. Weiss, David M. Weir, Debbie E. Harrington, Ashley Van Driesche, David Satzer, Giacomo Valle, Lee E. Miller, Nicholas G. Hatsopoulos, Jorge Gonzalez-Martinez, Peter C. Warnke, John E. Downey, Michael L. Boninger, Jennifer L. Collinger, Robert A. Gaunt   +21 more
openaire   +2 more sources

A Roadmap for Implanting Electrode Arrays to Evoke Tactile Sensations Through Intracortical Stimulation

Human Brain Mapping, Volume 45, Issue 18, December 15, 2024.
Functional imaging of the somatosensory cortex in people with spinal cord injury enabled planning for precise electrode array placement in the brain for a brain–computer interface. Stimulation through electrodes in the somatosensory cortex generated sensations of touch in digits that matched the functional imaging results used for placement.
John E. Downey, Hunter R. Schone, Stephen T. Foldes, Charles Greenspon, Fang Liu, Ceci Verbaarschot, Daniel Biro, David Satzer, Chan Hong Moon, Brian A. Coffman, Vahab Youssofzadeh, Daryl Fields, Taylor G. Hobbs, Elizaveta Okorokova, Elizabeth C. Tyler‐Kabara, Peter C. Warnke, Jorge Gonzalez‐Martinez, Nicholas G. Hatsopoulos, Sliman J. Bensmaia, Michael L. Boninger, Robert A. Gaunt, Jennifer L. Collinger   +21 more
wiley   +1 more source

Advanced flexible brain‐computer interfaces and devices for the exploration of neural dynamics

Brain‐X, Volume 2, Issue 4, December 2024.
This perspective paper discusses how the development of flexible neural interfaces and devices can overcome the limitations of traditional neurotechnology and could revolutionize investigations into neural principles behind intelligence, consciousness, and behavior.
Pancheng Zhu, Mengxia Yu, Mingzheng Wu, Yiyuan Yang   +3 more
wiley   +1 more source

Direct visualization of microwires in hybrid depth electrodes using high‐resolution photon‐counting CT

Epilepsia Open, Volume 9, Issue 6, Page 2518-2521, December 2024.
Abstract Hybrid depth electrodes are increasingly being used for epilepsy monitoring and human neurophysiology research. Microwires extending from the tip of the Behnke‐Fried (BF) electrode into (sub)cortical areas allow to isolate single neurons and perform microstimulation.
Steven Smeijers, Walter Coudyzer, Elina Keirse, Vasiliki Bougou, Thomas Decramer, Tom Theys   +5 more
wiley   +1 more source

Neural–Computer Interfaces: Theory, Practice, Perspectives

Applied Sciences
This review outlines the technological principles of neural–computer interface (NCI) construction, classifying them according to: (1) the degree of intervention (invasive, semi-invasive, and non-invasive); (2) the direction of signal communication ...
Ignat Dubynin, Maxim Zemlyanskov, Irina Shalayeva, Oleg Gorskii, Vladimir Grinevich, Pavel Musienko   +5 more
doaj   +1 more source

Long-term stability of sensitivity to intracortical microstimulation of somatosensory cortex

Journal of Neural Engineering, 2015
The dexterous manipulation of objects depends heavily on somatosensory signals from the limb. The development of anthropomorphic robotic arms and of algorithms to decode intended movements from neuronal signals has stimulated the need to restore somatosensation for use in upper-limb neuroprostheses.
Thierri, Callier, Erik W, Schluter, Gregg A, Tabot, Lee E, Miller, Francesco V, Tenore, Sliman J, Bensmaia   +5 more
openaire   +2 more sources

Behavioral detection of intra-cortical microstimulation in the primary and secondary auditory cortex of cats

Frontiers in Systems Neuroscience, 2015
Although neural responses to sound stimuli have been thoroughly investigated in various areas of the auditory cortex, the results electrophysiological recordings cannot establish a causal link between neural activation and brain function.
Zhenling eZhao, Yongchun eLiu, Lanlan eMa, Yu eSato, Ling eQin   +4 more
doaj   +1 more source

Linking spatially distributed neuronal activation overlap to the limits of perceptual discrimination in rodent primary somatosensory cortex

Frontiers in Computational Neuroscience
IntroductionIntracortical microstimulation (ICMS) of the primary somatosensory cortex can evoke localized tactile percepts, yet the spatial factors that influence perceptual discrimination remain poorly defined.
Madison Jiang, Joseph J. Pancrazio, Thomas J. Smith   +2 more
doaj   +1 more source