Results 71 to 80 of about 15,463 (165)

FMRI activity in the macaque cerebellum evoked by intracortical microstimulation of the primary somatosensory cortex: evidence for polysynaptic propagation. [PDF]

PLoS ONE, 2012
Simultaneous electrical microstimulation (EM) and functional magnetic resonance imaging (fMRI) is a useful tool for probing connectivity across brain areas in vivo.
Teppei Matsui, Kenji W Koyano, Keita Tamura, Takahiro Osada, Yusuke Adachi, Kentaro Miyamoto, Junichi Chikazoe, Tsukasa Kamigaki, Yasushi Miyashita   +8 more
doaj   +1 more source

Long‐Term Stable Neural Interfaces with Nanoporous Graphene Electrodes and Hybrid Polyimide‐Aluminium Oxide Encapsulation

Small Methods, Volume 9, Issue 12, December 1, 2025.
Flexible thin‐film neural microelectrodes combining nanoporous reduced graphene oxide and a PI/Al2O3 hybrid encapsulation maintained stable electrochemical performance after soaking in PBS at 57 °C for over 377 days while they sustained the injection of 1 billion biphasic current pulses at high charge density (1 mC cm−2).
Georgios Alexandros Katirtsidis, Xavier Illa, Nicola Ria, Elena del Corro, Eduard Masvidal Codina, Jose A. Garrido   +5 more
wiley   +1 more source

The functional consequences of chronic, physiologically effective intracortical microstimulation

, 2011
Many studies have demonstrated the ability of chronically implanted multielectrode arrays (MEAs) to extract information from the motor cortex of both humans and nonhuman primates. Similarly, many studies have shown the ability of intracortical microstimulation to impart information to the brain via a single or a few electrodes acutely implanted in ...
Rebecca A, Parker, Tyler S, Davis, Paul A, House, Richard A, Normann, Bradley, Greger   +4 more
openaire   +3 more sources

Toward Natural Limb Function: A New Era in Prosthetic Innovation

Annals of Neurology, Volume 98, Issue 5, Page 913-928, November 2025.
The past decade has witnessed groundbreaking clinical implementation of neuroprosthetic limbs driven by signals from peripheral targets (eg, nerves and muscle) and the brain to restore limb function for individuals with limb loss or impairment. In this review, we highlight recent key clinical trials in peripheral neuroprosthetic interfaces directly ...
Yucheng Tian, Dylan M. Wallace, Paul S. Cederna, Cynthia A. Chestek, Stephen W. P. Kemp   +4 more
wiley   +1 more source

Telemetry-controlled simultaneous stimulation-and-recording device (SRD) to study interhemispheric cortical circuits in rat primary somatosensory (SI) cortex

BMC Biomedical Engineering, 2019
Background A growing need exists for neuroscience platforms that can perform simultaneous chronic recording and stimulation of neural tissue in animal models in a telemetry-controlled fashion with signal processing for analysis of the chronic recording ...
John T. Ramshur, Bashir I. Morshed, Amy L. de Jongh Curry, Robert S. Waters   +3 more
doaj   +1 more source

A roadmap for implanting microelectrode arrays to evoke tactile sensations through intracortical microstimulation

medRxiv
Intracortical microstimulation (ICMS) is a method for restoring sensation to people with paralysis as part of a bidirectional brain-computer interface to restore upper limb function.
J. Downey, Hunter R. Schone, Stephen T. Foldes, Charles M. Greenspon, Fang Liu, Ceci Verbaarschot, Daniel Biro, David Satzer, Chan H. Moon, Brian A. Coffman, V. Youssofzadeh, Daryl P. Fields, Taylor G. Hobbs, Elizaveta V Okorokova, E. Tyler-Kabara, Peter C. Warnke, Jorge Gonzalez-Martinez, N. Hatsopoulos, S. Bensmaia, M. L. Boninger, Robert A. Gaunt, J. Collinger   +21 more
semanticscholar   +1 more source

Confirmation of the Enhancement Effect of ANCE Treatment on Functional Recovery of Manual Dexterity From Primary Motor Cortex (M1) Lesion in Adult Macaque Monkeys

Brain and Behavior, Volume 15, Issue 10, October 2025.
Together, an earlier pilot study and the current confirmatory study show that an autologous cellular therapy promotes beneficial, significant enhancement of manual dexterity recovery after lesion of the primary motor cortex. ABSTRACT Introduction A pilot study provided preliminary evidence indicating that peri‐lesional adult autologous neural cell ...
Camille Roux, Julie Savidan, Jean‐François Brunet, Jocelyne Bloch, Eric M. Rouiller, Eric Schmidlin, Mélanie Kaeser   +6 more
wiley   +1 more source

Characterizing Evoked Movement Patterns and Connectivity in Sensorimotor Cortex After Sensory Loss in Squirrel Monkeys

Journal of Comparative Neurology, Volume 533, Issue 10, October 2025.
Excitability to long‐train intracortical microstimulation in the primary somatosensory cortex after recovery from long‐term sensory loss tended to be altered but was not statistically different from that of normal and intact hemispheres. Cortical connection patterns of areas 3b and M1 were consistent with early findings, characterized by the presence ...
Hui‐Xin Qi, Chia‐Chi Liao, Jamie L. Reed, Iwona Stepniewska, Qimeng Wang, Jon H. Kaas   +5 more
wiley   +1 more source

Intracortical microstimulation of human somatosensory cortex is sufficient to induce perceptual biases

medRxiv
Time-order error, a psychophysical phenomenon in which the duration in between successive stimuli alters perception, has been studied for decades by neuroscientists and psychologists. To date, however, the locus of these effects is unknown.
Charles M. Greenspon, Natalya D. Shelchkova, Taylor G. Hobbs, S. Bensmaia, Robert A. Gaunt   +4 more
semanticscholar   +1 more source

Rewiring neural interactions by micro-stimulation

Frontiers in Systems Neuroscience, 2010
Plasticity is a crucial component of normal brain function and a critical mechanism for recovery from injury. In vitro, associative pairing of presynaptic spiking and stimulus-induced postsynaptic depolarization causes changes in the synaptic efficacy ...
James M Rebesco, Ian H Stevenson, Konrad Koerding, Konrad Koerding, Sara A Solla, Sara A Solla, Lee E. Miller, Lee E. Miller, Lee E. Miller   +8 more
doaj   +1 more source