Results 11 to 20 of about 5,738 (131)

Prevalence, volume, and clinical correlates of intracranial arteriosclerosis among patients with cognitive complaints: a clinic‐based study [PDF]

Alzheimers Dement
Abstract Background Intracranial arteriosclerosis increases the risk of dementia in the general population, but no published studies have determined its clinical value for the diagnosis of vascular cognitive impairment in a memory clinic setting. Method We included 317 patients (mean age: 69.9 years, 44% female) who attended the Erasmus MC Alzheimer ...
MERDASSA O, Raso F, Vernooij M, Evans T, Van den Berg E, Bos D, Wolters F.   +6 more
europepmc   +4 more sources

Intracranial arteriosclerosis: determinants and clinical consequences [PDF]

, 2023
Vaatverkalkingen, of arteriosclerose, zijn afzettingen van mineralen in het vaatstelsel, meestal in de vorm van hydroxyapatiet. In de vaatwant komen ze met name voor in atherosclerotische plaque in de tunica intima, of in de omliggende lamina elastica interna (IEL) of tunica media.
Tim Cornelis van den Beukel
openaire   +4 more sources

Intracranial arteriosclerosis and the risk of dementia: A population‐based cohort study [PDF]

Alzheimer's & Dementia, 2023
AbstractBACKGROUNDThe impact of intracranial arteriosclerosis on dementia remains largely unclear.METHODSIn 2339 stroke‐free and dementia‐free participants (52.2% women, mean age 69.5 years) from the general population, we assessed intracranial carotid artery calcification (ICAC) and vertebrobasilar artery calcification (VBAC) as proxy for ...
van den Beukel, Tim C., Wolters, Frank J., Siebert, Uwe, Spiering, Wilko, Ikram, M. Arfan, Vernooij, Meike W., de Jong, Pim A., Bos, Daniel   +7 more
openaire   +4 more sources

Morphological Subtypes of Intracranial Internal Carotid Artery Arteriosclerosis and the Risk of Stroke [PDF]

Stroke, 2022
Background: Accumulating evidence highlights the existence of distinct morphological subtypes of intracranial carotid arteriosclerosis. So far, little is known on the prevalence of these subtypes and subsequent stroke risk in the general population.
Tim C. van den Beukel, Janine E. van der Toorn, Meike W. Vernooij, Maryam Kavousi, Ali C. Akyildiz, Pim A. de Jong, Aad van der Lugt, M. Kamran Ikram, Daniel Bos   +8 more
openaire   +6 more sources

P2‐416: INTRACRANIAL ARTERIOSCLEROSIS AND BRAIN STRUCTURE IN AGING [PDF]

Alzheimer's & Dementia, 2019
Elisabeth J. Vinke, Pinar Yilmaz, Rahman Fakhry, Kilian Frenzen, Silvan Licher, Maryam Kavousi, M. Arfan Ikram, Meike W. Vernooij, Daniel Bos   +8 more
openaire   +2 more sources

Atherosclerosis enhances the efficacy of liposome-encapsulated bromocriptine in reducing the incidence of prolactinemia in pituitary tumors [PDF]

Journal of Nanobiotechnology
Intranasal drug delivery via nanocarriers has long been a research focus for enhancing drug concentration in the brain. However, the strategy of exploiting blood–brain barrier (BBB) alterations in atherosclerotic mouse models to enhance nanoparticle ...
Zhe Zhang, Guangyu Jia, Qi Wang, Yamei Yu, Xiaolong Tang, Heqing Zheng, Xinyu Yang, Yao Xiao, Yangrui Ou, Jingjing Jiang, Hua Guo, Ye Wang, Shiyong Li   +12 more
doaj   +2 more sources

Ventriculomegaly without elevated intracranial pressure? Normal pressure hydrocephalus as a disorder of the cerebral windkessel [PDF]

Frontiers in Neurology
ObjectiveNormal pressure hydrocephalus (NPH) is characterized by ventriculomegaly without elevations in intracranial pressure (ICP). One way of viewing hydrocephalus is as a disorder of the cerebral windkessel.
Racheed Mani, Racheed Mani, Jade Basem, Liu Yang, Liu Yang, Nahid Shirdel Abdolmaleki, Anand Ravishankar, Susan Fiore, Petar Djuric, Michael Egnor   +9 more
doaj   +2 more sources

Impact of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on intracranial atherosclerotic plaque characteristics and low density lipoprotein-cholesterol (LDL-C) reduction: a real-world observational study [PDF]

PeerJ
Background and purpose The combination of PCSK9 inhibitors and moderate statin therapy effectively stabilizes intracranial atherosclerotic plaques in patients with intracranial atherosclerotic stenosis (ICAS).
Zhenzhen Li, Xiaohui Li, Yiting Zhang, Jingwen Qi, Lifan Ji, Shuo Li, Mengmeng Gu, Yukai Liu, Yuqiao Zhang, Yanping Mei, Meng Wang, Junshan Zhou, Mouxiao Su, Lin Zhu, Qiwen Deng   +14 more
doaj   +3 more sources

Feasibility of calcium scoring of intracranial arteries as a measure of arteriosclerosis in stroke patients

, 2011
Purpose: Little is known about quantification of intracranial arteriosclerosis in stroke patients. CT angiography (CTA) is becoming part of the routine CT stroke work-up and may offer a way to quantify intracranial calcium burden (Figure 1).
Nikola Gotovac
openaire   +2 more sources

Review of theories into the pathogenesis of normal pressure hydrocephalus [PDF]

BMJ Neurology Open
Normal pressure hydrocephalus (NPH) represents a unique form of hydrocephalus characterised by the paradox of ventriculomegaly without significant elevations in intracranial pressure, with the clinical triad of gait instability, cognitive impairment, and
Liu Yang, Racheed Mani, Jade Basem, Susan Fiore, Petar Djuric, Michael Egnor   +5 more
doaj   +2 more sources