Results 101 to 110 of about 270,501 (180)

NIHSS and Large Artery Atherosclerosis Affect Efficacy of Dual Antiplatelet Therapy Versus Alteplase for Minor Stroke

Brain and Behavior, Volume 16, Issue 10, October 2026.
ABSTRACT Background Dual antiplatelet therapy (DAPT) was noninferior to alteplase in nondisabling minor stroke (NIHSS 0 to 5). Given potential benefit of DAPT in minor stroke with large artery atherosclerosis (LAA) and of alteplase in stroke with NIHSS 4–5, we hypothesize that neurological deficit and LAA may affect efficacy of DAPT versus alteplase in
Yu Cui, Zi‐Ang Li, Chao He, Hui‐Sheng Chen   +3 more
wiley   +1 more source

Comparative Effectiveness of Intravenous Tenecteplase versus Alteplase in Posterior Circulation Ischemic Stroke: A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 16, Issue 10, October 2026.
Visual summary of the comparative efficacy and safety of intravenous tenecteplase versus alteplase in posterior circulation ischemic stroke. ABSTRACT Background Posterior circulation ischemic stroke (PCIS) is associated with substantial morbidity and mortality, and the optimal intravenous thrombolytic strategy in this subgroup remains unclear.
Shaheer Bin Shafiq, Ammad Uddin, Muhammad Hussain, Ghulam Taha Khan, Muhammad Hassan, Muhammad Junaid Razzak, Mominah Majid, Faisal Islam, Umer Ahmed, Ahmed Anwaar Uddin, Hasibullah Aminpoor, Muhammad Ahmed   +11 more
wiley   +1 more source

Computerised tomography indices of raised intracranial pressure and traumatic brain injury severity in a New Zealand sample [PDF]

, 2012
After traumatic brain injury (TBI) complex cellular and biochemical processes occur¹ including changes in blood flow and oxygenation of the brain; cerebral swelling; and raised intracranial pressure (ICP).² This can dramatically worsen the damage³ and ...
Feigin, Valery L., Theadom, Alice, Starkey, Nicola J., Barker-Collo, Suzanne, Kahan, Michael   +4 more
core  

CYP2C19 Genotyping to Guide Clopidogrel Prescribing for Neurovascular Indications: A Survey of Institutional Approaches

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 937-942, October 2026.
Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is commonly used for secondary prevention following acute ischemic stroke (AIS) and neurointerventional procedures. However, the efficacy of clopidogrel is reduced in carriers of CYP2C19 no‐function alleles.
Rachael M. Stone, Glenda Hoffecker, April Schultz, Brittney H. Davis, Salma A. Bargal, Amber L. Beitelshees, Nihal El Rouby, Madeline Norris, Kevin J. Rodriguez, Nita Limdi, Larisa H. Cavallari, Craig R. Lee   +11 more
wiley   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 9, Page 2138-2155, October 2026.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland, Samuel J. Belfer, Christine K. Fox, Samantha L. Irwin, Rachel Vassar, Ann Oh, Sruthi Ilangovan, Amy A. Gelfand   +7 more
wiley   +1 more source

Temporal changes in symptomatic intracranial arterial disease: a longitudinal high-resolution vessel wall imaging study

Frontiers in Neurology
IntroductionThe temporal dynamics of the vessel wall in intracranial arterial disease (ICAD) may differ depending on the etiology. We investigated temporal changes in narrowed intracranial arteries after ischemic stroke using serial high-resolution ...
Dong-Wan Kang, Dong-Wan Kang, Jonguk Kim, Jonguk Kim, Do Yeon Kim, Do Yeon Kim, Do Yeon Kim, Sung Hyun Baik, Cheolkyu Jung, Bijoy K. Menon, Jae W. Song, Moon-Ku Han, Hee-Joon Bae, Beom Joon Kim   +13 more
doaj   +1 more source

Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde, Jessem Landoulsi, Xavier Houard   +2 more
wiley   +1 more source

Serum lipid profiles and the burden of polyvascular atherosclerosis: a cross-sectional CTA-based study in a Chinese cohort

Journal of Stroke and Cerebrovascular Diseases
Background and aims: Coexisting atherosclerosis across vascular territories is a critical facet of multimorbidity in aging populations and is associated with adverse outcomes, yet it often remains underdiagnosed.
Jing Lu, MD, Fa Lin, MD, Jiadi Weng, MD, Jian Lyu, MD, Lelin Zhang, MD, Wenxiong Song, MD, Bingcheng Zhu, MD, Miao Ma, MD, Huiwen Xu, MD, Jionghao Xue, MD, Minghao Liu, MD, Yunxin Zhang, MD, Yu Chen, MD, Runting Li, MD, Ke Wang, MD, Haiyang Liu, MD, Xiaolin Chen, MD, Jizong Zhao, MD, Jie Liu, MD   +18 more
doaj   +1 more source

The natural history of intracranial carotid artery atherosclerosis

, 2005
Intracranial atherosclerosis is the cause of a significant number of strokes. Despite maximal medical therapy, this disease continues to carry a poor prognosis.
Meyers, Philip M, Connolly, Jr, E Sander, Lavine, Sean D, Wilson, David A, Komotar, Ricardo J, Mocco, J   +5 more
core   +2 more sources

Atherosclerosis: Pathogenesis and treatment options

, 2020
Atherosclerosis is a multifactorial process. The onset of the pathogenesis is thought to stem from endothelial injury leading to endothelial dysfunction. The prevention of atherosclerosis is primarily by implementing exercise and diet plans. Some natural
Njálsdóttir, Andrea
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