Results 91 to 100 of about 26,399 (197)
IntroductionThe temporal dynamics of the vessel wall in intracranial arterial disease (ICAD) may differ depending on the etiology. We investigated temporal changes in narrowed intracranial arteries after ischemic stroke using serial high-resolution ...
Dong-Wan Kang +13 more
doaj +1 more source
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley +1 more source
Abstract INTRODUCTION Genome‐wide association studies (GWAS) have identified 80+ genetic loci associated with Alzheimer's disease (AD), enabling the development of polygenic risk scores (PRS). However, the predictive accuracy of PRS in diverse populations remains low.
Meri Okorie +9 more
wiley +1 more source
Plasma proteomics of cerebrovascular disease, cognitive decline, and clinical outcomes
Abstract INTRODUCTION The plasma proteomic signatures underlying cerebrovascular disease (CeVD) remains poorly understood. METHODS A total of N = 2534 participants across two independent longitudinal Southeast‐Asian cohorts were included. We profiled 1441 baseline plasma proteins in a memory‐clinic cohort (N = 518), followed‐up for 4 years.
Ming Ann Sim +22 more
wiley +1 more source
Abstract INTRODUCTION Subclinical cardiovascular remodeling may impair cerebral hemodynamics and contribute to dementia, but the perfusion features linking subclinical cardiovascular dysfunction to cerebrovascular injury remain unclear. METHODS We studied 1748 UK Biobank participants with cardiac magnetic resonance imaging (MRI), arterial spin labeling
Ye Zhang +11 more
wiley +1 more source
MIND diet, cerebrovascular health, and cognition among community‐dwelling older adults
Abstract INTRODUCTION Understanding of the Mediterranean–Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Disease (MIND) diet's association with cerebral arteriosclerosis, and whether cerebrovascular outcomes link diet to cognition is limited. METHODS We included 713 participants (81 ± 7.2 years old, 77% female, 16 ± 2.9 years
Puja Agarwal +11 more
wiley +1 more source
Schematic representation of the balloon passage via microwire navigation technology. ABSTRACT This case presents that balloon passage via microwire navigation technology could be a beneficial option for patients with severe MCA stenosis, with the diameter of the proximal blood vessel in the stenotic segment is < 1.5 mm and there is antegrade blood flow.
Yang Gao +10 more
wiley +1 more source
ABSTRACT Diabetic striatopathy is a reversible cause of acute chorea occurring in patients with poorly controlled diabetes mellitus, including those even with complex comorbidities like HIV. Timely neuroimaging and prompt metabolic correction are crucial, emphasizing the need for high clinical suspicion.
Kojo Awotwi Hutton‐Mensah +5 more
wiley +1 more source
Background and purpose Cerebral large artery and small vessel diseases are related to different pathogenetic mechanisms and have different risk factor profile.
Yongjun Wang +13 more
doaj +1 more source
In this large real‐world propensity‐matched analysis, tirzepatide demonstrated superior reductions in mortality, hospitalizations, and cardiorenal outcomes versus dulaglutide in HFpEF patients, with a favorable safety profile. ABSTRACT Background No direct head‐to‐head trials compare tirzepatide and dulaglutide in heart failure with preserved ejection ...
Ibrahim Khalil +8 more
wiley +1 more source

