Results 91 to 100 of about 26,399 (197)

Temporal changes in symptomatic intracranial arterial disease: a longitudinal high-resolution vessel wall imaging study

open access: yesFrontiers in Neurology
IntroductionThe temporal dynamics of the vessel wall in intracranial arterial disease (ICAD) may differ depending on the etiology. We investigated temporal changes in narrowed intracranial arteries after ischemic stroke using serial high-resolution ...
Dong-Wan Kang   +13 more
doaj   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 16, 18 August 2026.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Cross‐ancestry polygenic risk scores enhance Alzheimer's disease risk prediction in multiethnic cohorts

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Genome‐wide association studies (GWAS) have identified 80+ genetic loci associated with Alzheimer's disease (AD), enabling the development of polygenic risk scores (PRS). However, the predictive accuracy of PRS in diverse populations remains low.
Meri Okorie   +9 more
wiley   +1 more source

Plasma proteomics of cerebrovascular disease, cognitive decline, and clinical outcomes

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION The plasma proteomic signatures underlying cerebrovascular disease (CeVD) remains poorly understood. METHODS A total of N = 2534 participants across two independent longitudinal Southeast‐Asian cohorts were included. We profiled 1441 baseline plasma proteins in a memory‐clinic cohort (N = 518), followed‐up for 4 years.
Ming Ann Sim   +22 more
wiley   +1 more source

Cerebral perfusion features linking subclinical cardiac and aortic dysfunction to vascular brain injury

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Subclinical cardiovascular remodeling may impair cerebral hemodynamics and contribute to dementia, but the perfusion features linking subclinical cardiovascular dysfunction to cerebrovascular injury remain unclear. METHODS We studied 1748 UK Biobank participants with cardiac magnetic resonance imaging (MRI), arterial spin labeling
Ye Zhang   +11 more
wiley   +1 more source

MIND diet, cerebrovascular health, and cognition among community‐dwelling older adults

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Understanding of the Mediterranean–Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Disease (MIND) diet's association with cerebral arteriosclerosis, and whether cerebrovascular outcomes link diet to cognition is limited. METHODS We included 713 participants (81 ± 7.2 years old, 77% female, 16 ± 2.9 years
Puja Agarwal   +11 more
wiley   +1 more source

Balloon Passage via Microwire Navigation Technology for Severe Stenosis of Middle Cerebral Artery: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
Schematic representation of the balloon passage via microwire navigation technology. ABSTRACT This case presents that balloon passage via microwire navigation technology could be a beneficial option for patients with severe MCA stenosis, with the diameter of the proximal blood vessel in the stenotic segment is < 1.5 mm and there is antegrade blood flow.
Yang Gao   +10 more
wiley   +1 more source

Diabetic Striatopathy in a Middle‐Aged African Woman With Poorly Controlled Type 2 Diabetes Mellitus and HIV Coinfection—A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Diabetic striatopathy is a reversible cause of acute chorea occurring in patients with poorly controlled diabetes mellitus, including those even with complex comorbidities like HIV. Timely neuroimaging and prompt metabolic correction are crucial, emphasizing the need for high clinical suspicion.
Kojo Awotwi Hutton‐Mensah   +5 more
wiley   +1 more source

Differential associations of lipoprotein(a) level with cerebral large artery and small vessel diseases

open access: yesStroke and Vascular Neurology
Background and purpose Cerebral large artery and small vessel diseases are related to different pathogenetic mechanisms and have different risk factor profile.
Yongjun Wang   +13 more
doaj   +1 more source

Superior Cardiorenal Protection With Tirzepatide Over Dulaglutide in Heart Failure With Preserved Ejection Fraction: A Large‐Scale Propensity Score–Matched Real‐World Analysis

open access: yesClinical Cardiology, Volume 49, Issue 8, August 2026.
In this large real‐world propensity‐matched analysis, tirzepatide demonstrated superior reductions in mortality, hospitalizations, and cardiorenal outcomes versus dulaglutide in HFpEF patients, with a favorable safety profile. ABSTRACT Background No direct head‐to‐head trials compare tirzepatide and dulaglutide in heart failure with preserved ejection ...
Ibrahim Khalil   +8 more
wiley   +1 more source

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